YYYY@YYYY I am sensitive to a number of drugs. What are the interactions/side effects of Tizanidine? They noticed a little arthritis in my back, and I normally don't sleep very long in one position.. I am sensitive to a number of medications, so.... I try to stick with vitamins instead. But it cannot be for every health challenge. I may need to go on Aricept. I am 74 yrs old, 110lbs. I am also depressed, unfortunately. Not fun!