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Diabetic, What Is Defect In Insulin And The Effects Of Glucose Metabolism Who Is Non Insulin Dependant?

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Posted on Thu, 3 Oct 2013
Question: what is the defect in insulin and the effects of glucose metabolism with someone who is diabetic 2 and is non insulin dependent
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Answered by Dr. Dr. Shruti Rijhwani (58 minutes later)
Brief Answer:
Insulin is not affected in type 2 Diabetes.

Detailed Answer:
Dear Madam,

Thank you for posting you query.

Well looking into your question Type 2 Diabetesis a metabolic disorder . It is characterized by high blood glucose due to peripheral insulin resistance that is the insulin that is produced by pancreas in the body is not able to act on peripheral tissues so it remains unutilised and then can secondarily result in relative insulin deficiency due to organ damage .So basically there is no defect in insulin production .

In absolute insulin deficiency due to destruction of islet cells in the pancreas thus the blood sugar rises due to lack of insulin but the action of insulin on peripheral tissues is preserved .

Take care.

Dr. Shruti
Note: For further follow-up, discuss your blood glucose reports with our diabetologist. Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr. Shruti Rijhwani

Rheumatologist

Practicing since :2008

Answered : 2366 Questions

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Diabetic, What Is Defect In Insulin And The Effects Of Glucose Metabolism Who Is Non Insulin Dependant?

Brief Answer:
Insulin is not affected in type 2 Diabetes.

Detailed Answer:
Dear Madam,

Thank you for posting you query.

Well looking into your question Type 2 Diabetesis a metabolic disorder . It is characterized by high blood glucose due to peripheral insulin resistance that is the insulin that is produced by pancreas in the body is not able to act on peripheral tissues so it remains unutilised and then can secondarily result in relative insulin deficiency due to organ damage .So basically there is no defect in insulin production .

In absolute insulin deficiency due to destruction of islet cells in the pancreas thus the blood sugar rises due to lack of insulin but the action of insulin on peripheral tissues is preserved .

Take care.

Dr. Shruti