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Does Atacand Interact With Amlodipine And Irbesartan?

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Posted on Mon, 4 Jan 2016
Question: I had been taking Atacand 32 mgs and Amlodipine 10 mgs for high blood pressure. I recently switched to Irbesartan 150 mgs and still taking Amlodipine 10 mgs with it as with the Atacand. I'm looking for a drug or drug combination to lower my blood pressure with as small side effects as possible. Can you advise on this?
doctor
Answered by Dr. Ilir Sharka (38 minutes later)
Brief Answer:
I would explain as follows:

Detailed Answer:
Hello!

I am glad to hear from you on HCM again!

As every different class of anti hypertensive therapy has its different adverse effects, it is important to find the most appropriate or compatible therapy based on every individual characteristics (accounting for potential commodities, responsible mechanisms of hypertension, known hypersensibility, and other concomitant therapies, etc.).

Please could you provide me with information regarding two more points:

1. Have you experienced any adverse effects while taking your actual therapy?
I would like to know concrete evidence in order to be possible for me to recommend you more safe anti hypertensive combinations, without side effects.

2.Has your actual anti hypertensive therapy shown to be effective in controlling your blood pressure? What are your actual blood pressure values?

Please provide me with more information about the above mentioned issues. I would be glad to be helpful in guiding you the most appropriate anti hypertensive therapy.

Hope you will find this answer helpful!

Kind regards!

Dr. Iliri
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Ilir Sharka (5 hours later)
Thank you for responding. My blood pressure with Atacand and Irbesartan with Amlodipine is an average of 136/85 for both meds. Does taking Amlodipine help to lower blood pressure? I don't know if any adverse reactions are coming from the blood pressure drugs or from Ibuprofen. The 2 adverse effects that I have - is trouble sleeping and digestive issues.
doctor
Answered by Dr. Ilir Sharka (9 hours later)
Brief Answer:
I would explain as follows:

Detailed Answer:
Hello again!

Thank you for the additional information provided!

I would explain that amlodipine helps lowering your blood pressure as it is an antihypertensive drug (calcium channel blocker), while ibuprofen can lead to a raise in your blood pressure as an adverse effect.

No one of these drugs is related to trouble sleeping as an adverse effects.

The diggestive issues can be relate to all of them:

-Ibuprofen can cause nausea, dyspepsia (indigestion), heartburn, vomiting and constipation
-amlodipine can cause constipation, rarely nausea and abdominal pain.
-irbesartan could be related to dyspepsia and diarrhea

Ibuprofen seems to show a higher frequence of diggestive adverse effects than the other drugs.

I recommend discussing with your doctor on the above issues.

Regarding the sleep disorder, I recommend discussing with a neurologist and start the proper therapy. Melatonine could help regulate your physiological cycle (day-night).

Hope to have been of help!

Greetings!

Dr. Iliri
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Ilir Sharka (10 hours later)
My doctor has said that I am pre-diabetic. Would Atacand 32 mgs and Amlodipine 10 mgs or Irbesartan 150 mgs and Amlodipine 10 mgs be worse on the kidneys or liver then other high blood pressure drugs? If I am pre-diabetic, then I would want to take high blood pressure drugs that do not affect the liver or kidneys.

Thank you
doctor
Answered by Dr. Ilir Sharka (2 hours later)
Brief Answer:
There is nothing to worry about!

Detailed Answer:
Hello again!

Regarding your concern, you should know that as long as your liver function tests and your kidney function tests result normal, there is nothing to worry about.

So it is safe to use amlodipine, irbesartan or atacand in this clinical condition, if you have a normal liver and kidney function.

Hope to have been of help!

Greetings!

Dr. Iliri
Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
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Dr. Ilir Sharka

Cardiologist

Practicing since :2001

Answered : 9544 Questions

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Does Atacand Interact With Amlodipine And Irbesartan?

Brief Answer: I would explain as follows: Detailed Answer: Hello! I am glad to hear from you on HCM again! As every different class of anti hypertensive therapy has its different adverse effects, it is important to find the most appropriate or compatible therapy based on every individual characteristics (accounting for potential commodities, responsible mechanisms of hypertension, known hypersensibility, and other concomitant therapies, etc.). Please could you provide me with information regarding two more points: 1. Have you experienced any adverse effects while taking your actual therapy? I would like to know concrete evidence in order to be possible for me to recommend you more safe anti hypertensive combinations, without side effects. 2.Has your actual anti hypertensive therapy shown to be effective in controlling your blood pressure? What are your actual blood pressure values? Please provide me with more information about the above mentioned issues. I would be glad to be helpful in guiding you the most appropriate anti hypertensive therapy. Hope you will find this answer helpful! Kind regards! Dr. Iliri