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Does Flexeril Interact With Remeron?

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Posted on Mon, 13 Feb 2017
Question: I saw a dr in an urgent care facility and was prescribed flexeril for a muscle strain.
I take 7.5 mgs of remeron at night to help with insomnia. I am concerned about the possibility of serotonin syndrome if I take the flexeril. Is it really safe to take these meds together?
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Answered by Dr. Dr. Michelle Gibson (53 minutes later)
Brief Answer:
should not be used together

Detailed Answer:
HI, thanks for using healthcare magic

No, it is not safe to use these medications together.

As you stated they both affect the level of serotonin , therefore putting you at risk of the serotonin syndrome.
An alternative would need to be used for one of these medications


Baclofen, XXXXXXX , valium are alternative muscle relaxants that do not increase serotonin levels.

It would be best to get an alternative prescription from your doctor.

I hope this helps, feel free to ask any other questions
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr. Michelle Gibson

General & Family Physician

Practicing since :2001

Answered : 16835 Questions

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Does Flexeril Interact With Remeron?

Brief Answer: should not be used together Detailed Answer: HI, thanks for using healthcare magic No, it is not safe to use these medications together. As you stated they both affect the level of serotonin , therefore putting you at risk of the serotonin syndrome. An alternative would need to be used for one of these medications Baclofen, XXXXXXX , valium are alternative muscle relaxants that do not increase serotonin levels. It would be best to get an alternative prescription from your doctor. I hope this helps, feel free to ask any other questions