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Does Hyoscyamine Interact With Reglan?

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Posted on Thu, 11 May 2017
Question: Took hyoscyamine for diarrhea and a few hours later, reglan. Got HORRIBLE stomach pains. I have IBS with alternating constipation, vomiting, and diarrhea. Every test in the book done. Is there an interaction? What about bentyl?
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Answered by Dr. Shafi Ullah Khan (1 hour later)
Brief Answer:
Supportive care

Detailed Answer:
Thank you for asking
I read your question and i understand your concern. IBS is diagnosis of exclusion and labelled only when all tests are positive. So this diarrhea predominant IBS needs mostly diet and lifestyle changes for the relief. Use of reglan has worsened diarrhea and should not have been taken. Hyoscyamine and antispasmodics like eg, peppermint oil, pinaverium, trimebutine, cimetropium/dicyclomine, TCAs like amitriptyline , anti diarrheals like loperamide can be tried.

But more important is diet lifestyle adjustment. More fiber, more fluids, less dairy, no spices, less fatty foods, least processed canned foods, least chocolates, least coffee tea cola alcohol etc, More probiotics, more yogurt with peppermint in it will help IBS symptoms. Take BRAT diet ( Banana, rice, applesauce and toast) when diarrhea is there.

I hope it helps. Take good care of yourself and dont forget to close the discussion please.

Regards
Khan
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shafi Ullah Khan

General & Family Physician

Practicing since :2012

Answered : 3613 Questions

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Does Hyoscyamine Interact With Reglan?

Brief Answer: Supportive care Detailed Answer: Thank you for asking I read your question and i understand your concern. IBS is diagnosis of exclusion and labelled only when all tests are positive. So this diarrhea predominant IBS needs mostly diet and lifestyle changes for the relief. Use of reglan has worsened diarrhea and should not have been taken. Hyoscyamine and antispasmodics like eg, peppermint oil, pinaverium, trimebutine, cimetropium/dicyclomine, TCAs like amitriptyline , anti diarrheals like loperamide can be tried. But more important is diet lifestyle adjustment. More fiber, more fluids, less dairy, no spices, less fatty foods, least processed canned foods, least chocolates, least coffee tea cola alcohol etc, More probiotics, more yogurt with peppermint in it will help IBS symptoms. Take BRAT diet ( Banana, rice, applesauce and toast) when diarrhea is there. I hope it helps. Take good care of yourself and dont forget to close the discussion please. Regards Khan