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Does Nattokinase Interact With Daflon?

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Posted on Wed, 16 Nov 2016
Question: I have venous insufficiency and venous insufficiency caused by I believe an injection of depo provera that made a very mild case of reflux that I has a lot worse. It's been since May 18th, 2016 that I received the depo. I've also read that depo or progesterone can cause weeking of the leg ligaments and muscle further exacerbating the problem. Is this true? Also is there any hope that my insufficiency will improve once is completely out say around late December or late January? Finally, I have been taking Daflon 500 along with Horse chestnut twice a day to help with managing the symptoms of my insufficiency, can I also add to that Nattokinase or will that have too much of a blood thinning effect with these other supplements putting me at risk for internal bleeding? Thank you
doctor
Answered by Dr. Michelle Gibson James (1 hour later)
Brief Answer:
daflon does not thin the blood or increase bleeding risk

Detailed Answer:
HI, thanks for using healthcare magic

If you received depo injections over a prolonged period of time, then it is definitely possible that it contributed to your venous disease.

If only one dose of the depo was received then this link is not as likely.

Thrombophletitis (inflammation of the veins) is one of the side effects of continued use of this medication but it thought to occur in less than 10% of persons using it (10 out of 100)

The inflamed veins are more likely to result in venous insufficiency.

The half life of a drug is the time it takes for the amount of drug in the body to decrease by half. It takes approximately 3 to 4 half lives for a drug to be completely eliminated.
The half life of depo is 50 days.
This means that it would take approximately 5 to near 7 months for complete elimination but the levels would be very low before this point.

If the depo caused damage to the veins or surrounding areas in any way, then stopping it would prevent any further injury and some improvement may occur

There are no known interactions between daflon and nattokinase so they can be used together.
Daflon is not classified as a blood thinner. It works by reinforcing venous tone and reducing venous inflammation.
It is not going to thin out your blood or increase your risk of bleeding or interact with the nattokinase in that way.

I hope this helps, feel free to ask any other questions
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Michelle Gibson James (23 minutes later)
Thank you very much, what about combined with horse chestnut? I'm also taking horse chestnut. I didn't know that daflon could cause vein inflammation. How long after using it? I just started taking it, when should I stop?

doctor
Answered by Dr. Michelle Gibson James (12 hours later)
Brief Answer:
be careful with horse chestnut and nattokinase

Detailed Answer:
Hi

Said daflon can reduce/decrease inflammation, this is one of the ways in which is helps in venous disease.
You should continue it.

In terms of the horse chestnut, it interacts with diabetic meds, lithium and blood thinners.
The fact that it can also slow down clotting may mean that you would have to be careful with the nattokinase which also reduces clotting.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Michelle Gibson James (14 days later)
I still have has a period. Does Daflon 500 stop or delay peroid? If so, can I use this as a natural way to control heavy period from adenomyosis, fibriods?
doctor
Answered by Dr. Michelle Gibson James (5 hours later)
Brief Answer:
Not a known effect of daflon

Detailed Answer:
Hi

This is not a known use of daflon. It has an effect on veins particularly those in the anus (hemorrhoids) or varicose veins

Bleeding from fibroid or endometriosis is currently not known to be related to this mode of action.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Michelle Gibson James (1 hour later)
Thank you Dr. I will close and review. I also wanted to know what options do I have for controlling heavy minstrel bleeding without hormones or invasive surgery?
doctor
Answered by Dr. Michelle Gibson James (8 hours later)
Brief Answer:
there are some herbal teas

Detailed Answer:
HI

sorry about the delayed reply

Heavy periods can be very upsetting.

There are some natural methods that are reported to help with heavy bleeding but it would be important to remember that these ideas would not be supported by medical studies. This means that they usefulness may or may not be true since it has not be investigated and their side effect profile is not known.

(1)teas with ginger, mustard seeds grounded or cinnamon tea made with soaking a stick,corriander seeds

If anything else is unclear can let me know
Note: For further inquiries on surgery procedure and its risks or complications book an appointment now

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
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Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 16808 Questions

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Does Nattokinase Interact With Daflon?

Brief Answer: daflon does not thin the blood or increase bleeding risk Detailed Answer: HI, thanks for using healthcare magic If you received depo injections over a prolonged period of time, then it is definitely possible that it contributed to your venous disease. If only one dose of the depo was received then this link is not as likely. Thrombophletitis (inflammation of the veins) is one of the side effects of continued use of this medication but it thought to occur in less than 10% of persons using it (10 out of 100) The inflamed veins are more likely to result in venous insufficiency. The half life of a drug is the time it takes for the amount of drug in the body to decrease by half. It takes approximately 3 to 4 half lives for a drug to be completely eliminated. The half life of depo is 50 days. This means that it would take approximately 5 to near 7 months for complete elimination but the levels would be very low before this point. If the depo caused damage to the veins or surrounding areas in any way, then stopping it would prevent any further injury and some improvement may occur There are no known interactions between daflon and nattokinase so they can be used together. Daflon is not classified as a blood thinner. It works by reinforcing venous tone and reducing venous inflammation. It is not going to thin out your blood or increase your risk of bleeding or interact with the nattokinase in that way. I hope this helps, feel free to ask any other questions