
Does Vitamin C Interact With Allopurinol?

Increase risk of kidney stones
Detailed Answer:
Hi there,
You should avoid Vitamin C when using allopurinol because the combination of the two medications will significantly increase your risk of developing a kidney stone. However, this may only be demonstrated in people who are taking large amounts (>500 mg daily) of vitamin C.
I would recommend stopping the Vitamin C to decrease your risk of kidney stones. Allopurinol is a much better drug for the treatment of gout anyways. Actually, vitamin C was shown to have no effect on decreasing uric acid levels with and without allopurinol, and therefore, it is clinically ineffective in the treatment in gout.
There is some new research that demonstrates that vitamin C might reduce your risk of getting gout, but it has not effect on the treatment.
I hope this helps!

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