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How Long Does Pristiq Remain In The System?

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Posted on Wed, 7 Oct 2015
Question: How long does it take for pristiq to leave your system. I had a bad reaction to it of insomnia, hyperactivity,assertive and aggressive behavior. all of this on a 50 mg. extended release. I then started taking 25 mg. for several days and still had same side effects. In turn I cut that in half and was taking 12.5 mg for 4 days and now completely off for 2 days and still have these same effects. Please advise.
doctor
Answered by Dr. Divakara (1 hour later)
Brief Answer:
It will take 3 more days.

Detailed Answer:
Hi

Greetings from Dr Divakara P
Thanks for posting your query.

Well these are the adverse reactions of the drug.The adverse reactions shall wear off in few days.

See the half life of Pristiq is 11 hours. It means the body takes 11 hours to remove 50% of the drug . So by calculation it takes 66 hours to remove 96% of the drug from the body. So a total of around 5 days is required to remove 96% of the drug from the body.

2/days have elapsed so 3 more days to go. But the intensity of these adverse reactions starts reducing day by day.

I advise you to drink plenty of water.

Hope this information was useful to you.
Any clarification feel free to ask.

Regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Divakara (4 hours later)
Is there anything that I can take to counter the effects of the insomnia and would restoril be a good choice? Any side effects from this medicine that would interfere with the weaning process? Thank you
doctor
Answered by Dr. Divakara (1 hour later)
Brief Answer:
Can take Alprazolam

Detailed Answer:
Hi

You can take medicine like Alprazolam for 1-2 days but it is a prescription only drug. You need to get a prescription for this from your doctor.


No low dose of alprazolam for 2 days will not causes any significant side effects.

Regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Divakara (52 minutes later)
What dosage would you recommend to start? You do not like the restoril?
doctor
Answered by Dr. Divakara (53 minutes later)
Brief Answer:
Restoril also will do.

Detailed Answer:
HI

Restoril also will do, usually I advise my 15mg at bedtime . I think 2 days of medication will take care of your problem.

But again you need to get prescription from your doctor for Restoril.

Regards
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Divakara

Internal Medicine Specialist

Practicing since :2006

Answered : 2358 Questions

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How Long Does Pristiq Remain In The System?

Brief Answer: It will take 3 more days. Detailed Answer: Hi Greetings from Dr Divakara P Thanks for posting your query. Well these are the adverse reactions of the drug.The adverse reactions shall wear off in few days. See the half life of Pristiq is 11 hours. It means the body takes 11 hours to remove 50% of the drug . So by calculation it takes 66 hours to remove 96% of the drug from the body. So a total of around 5 days is required to remove 96% of the drug from the body. 2/days have elapsed so 3 more days to go. But the intensity of these adverse reactions starts reducing day by day. I advise you to drink plenty of water. Hope this information was useful to you. Any clarification feel free to ask. Regards.