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Is Dobutamine Support Advisable For A Patient With Respiratory Acidosis?

Posted on Mon, 18 Aug 2014

Question: My friends mother is a known case of Hypothyroidism, hypertension, Renal disease and is on a pacemaker since many years. She had a sudden loss of consciousness 2 weeks back, turned out that the pacemaker battery was faulty and she was admitted with edema, with decreased urine output and had an episode of VT and 2 days after this urine output was nil and creat went upto 4.5, she has respiratory acidosis on ABG and has septicemia and is on ventilator and has had four dialysis. at present her SGOT is 200 odd and LDH is above 600 and is on nor adrenaline support... Do u recommend dobutamine support?
XXXX

Answered by Dr. Rakesh Madhyastha (21 minutes later)

Brief Answer:
Dobutamine support

Detailed Answer:
Hello

Thanks for the query

What has happened to your friend's mother is very unfortunate. To help you I need to know a few more details

1. Dobutmaine infusion is started when blood pressure is low, it is the drug of choice in a patient with an ischemic heart like your friend's mother. Please let me know her current blood pressure. If it is below 90/60 then definitely she will require dobutamine.
2. If she is on the ventilator and there is respiratory acidosis then ventilator settings have to be changed to wash out carbon dioxide.
3. Dialysis looks to be transient, she might not require it once the blood pressure improves. Fall in urine output is directly proportional to the fall in blood pressure

I wish her a speedy recovery. If you have any further queries please get back to me

Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Rakesh Madhyastha (18 minutes later)

Thanks for ur reply
Her pressures had fallen down to 70/30 mmHg and she was put on dobutamine but why it was stopped we dont know and since then she is on Nor adrenaline.
Her last ABG showed PCo2 as 47

Answered by Dr. Rakesh Madhyastha (18 minutes later)

Brief Answer:
Septic shock

Detailed Answer:
Hello

Thanks for the query

Noradrenaline is usually preferred over dobutamine and dopamine in septic shock probably that's why it was stopped
Pco2 of 47 is still high, she should recover soon.
Please get back to me with the antibiotics and the dosages she is on currently and whether any cultures have grown any organism

I hope to hear from you soon

regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Rakesh Madhyastha (3 minutes later)

Thanks
She is on Linezolid and Teicoplanin and antifungal and no bugs have grown in the blood cultures till now!

Regards

Answered by Dr. Rakesh Madhyastha (54 minutes later)

Brief Answer:
Follow up

Detailed Answer:
Hello

Thanks for the query

Linezolid and Teicoplanin are higher antibiotics, which means that the doctors are trying their best to help her. Teicoplanin requires renal adjustment as her creatinine is high, I am sure they have taken that to consideration as well.

Regards

Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar