Sign-in to Ask A Doctor - 24x7
OR
Sign in with Google
Is IgG4 Value Of 2.16 A Cause For Concern?
Question: I have three symptoms, possibly related. Since Feb 2016 I have been experiencing balance issues linked to a problem with my inner ear on the right side. I saw an ENT, who conducted various tests, and referred me to a balance physio therapist, and things seem to be steadily improving.
However, I also have:
(a) persistently enlarged and uncomfortable tonsils (not constantly, but most days, and to varying degrees); and
(b) an IGG4 level of 2.16. For some reason the ENT ordered various tests and one of them was an IGG4 test. Unfortunately he doesn't know why the test was ordered, why the number is elevated, or how we should proceed to clarify what the elevated IGG4 result means.
If someone on this forum has experience with any of these issues, would you mind offering some advice?
Many thanks.
XXXX
However, I also have:
(a) persistently enlarged and uncomfortable tonsils (not constantly, but most days, and to varying degrees); and
(b) an IGG4 level of 2.16. For some reason the ENT ordered various tests and one of them was an IGG4 test. Unfortunately he doesn't know why the test was ordered, why the number is elevated, or how we should proceed to clarify what the elevated IGG4 result means.
If someone on this forum has experience with any of these issues, would you mind offering some advice?
Many thanks.
XXXX
Brief Answer:
No active treatment required if asymptomatic.
Detailed Answer:
Hi,
Thank you for your query.
1. Elevated IgG4 levels indicate a rare lymphoproliferative autoimmune disorder of unknown cause. The levels may also be raised in an acute illness.
2. Since this is an incidental finding, first routine treatment for the chronic tonsillitis should be done. No active treatment for the raised IgG4 levels is necessary at present. Repeat the test after a month.
3. Persistently elevated levels will respond to steroid treatment. A dose of prednisolone 1mg/kg/day tapered over a few weeks will suffice. A hematologist's opinion should be taken.
I hope that I have answered your query. If you have any further questions, I will be available to answer them.
Regards.
No active treatment required if asymptomatic.
Detailed Answer:
Hi,
Thank you for your query.
1. Elevated IgG4 levels indicate a rare lymphoproliferative autoimmune disorder of unknown cause. The levels may also be raised in an acute illness.
2. Since this is an incidental finding, first routine treatment for the chronic tonsillitis should be done. No active treatment for the raised IgG4 levels is necessary at present. Repeat the test after a month.
3. Persistently elevated levels will respond to steroid treatment. A dose of prednisolone 1mg/kg/day tapered over a few weeks will suffice. A hematologist's opinion should be taken.
I hope that I have answered your query. If you have any further questions, I will be available to answer them.
Regards.
Note: Consult an experienced Otolaryngologist / ENT Specialist online for further follow up on ear, nose, and throat issues - Book a Call now.
Above answer was peer-reviewed by :
Dr. Nagamani Ng
Answered by
Get personalised answers from verified doctor in minutes across 80+ specialties
