Is The HIV DUO 4th Generation Test Conclusive At 27 Days Post Exposure?

Posted on Mon, 19 Sep 2016

Question: Dear Dr,

I had a protected exposure around 30 days back.

I did hiv duo test at 14 days result was non reactive.

Then I repeated the hiv duo 4 the generation test on 27 th day it was nonreactive.

Finally I did the hiv dna pcr proviral test qualitative for hiv -1 on 28th day the result
Was Not detected.

I also did the hiv - 2 quantitative pcr

Test Principle : Real Time PCR viral load
Result :
Target Selected : 5' LTR region
Sensitivity : 100 IU/ml
Specimen : EDTA PLASMA

Result is below
HIV-2 (Quantitative) Below 100 IU/mL

I spoke to doctor and he said it is negative and also the lab doctor said it is negative.

Are the above dna pcr test for hiv 1 and 2 conclusive at 28 days post expour.

Answered by Dr. Bharatesh Devendra Basti (22 minutes later)

Brief Answer:
HIV negative.

Detailed Answer:
Hi
Thank you for query. Welcome to health care magic.
I have gone through the details and can make out your anxiety.

The chances of transmission of HIV by protected intercourse is nil. The risk is nil.

HIV 1&2 PCR tests negative after 10-14 days exposure is very sensitive.It is negative.
Duo test is also negative.
With the given description and test results you are free from HIV. You can allay fears of HIV.

You can get back for any clarification.
Thank you
Dr Bharatesh D Basti
Dermatologist and venereolgist

Above answer was peer-reviewed by : Dr. Nagamani Ng

Follow up: Dr. Bharatesh Devendra Basti (22 minutes later)

Dear Dr,

Kindly note on the 23rd day post exposure I had runny nose , fever and sore throat .

I went to ENT specialist he gave my sinsusitis medication as I had little facial pain and headache.

He did a cbc and the lymphocytes level came low it was 7 and crp or cpr came 13.

Is there anything to worry.

Every thing was fine in 3 to 4 days.

Answered by Dr. Bharatesh Devendra Basti (1 hour later)

Brief Answer:
Not due to HIV

Detailed Answer:
Hi
Thank you for follow up query.

The symptoms are non specific and do not suggest HIV.It may be due to simple respiratory infections. The test results also do not suggest HIV . You can repeat the tests if necessary.

You can get back for any clarification.
Thank you
Dr Bharatesh D Basti

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Above answer was peer-reviewed by : Dr. Vaishalee Punj