Brief Answer:
Requires thorough work up
Detailed Answer:
When significant unintentional
weight loss occurs in any individual, especially smokers , it is absolutely important to rule out worrisome causes. This entails a comprehensive evaluation in terms of a complete physical examination and tests (blood, X ray etc). Regarding the
goiter there are couple things that may connect the symptoms you are reporting :
1 If the goiter is producing excessive thyroid hormone =
hyperthyroidism, as evidenced from blood tests called TSH and free T4, then that can cause weight loss as one of the manifestations
2 If there is a cancer in the thyroid, then a consequence of that is potential weight loss. An
ultrasound is a good start and based upon findings such as the presence of nodules in the thyroid, may necessitate a
biopsy of the suspicious ones with a fine needle aspiration technique
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