
Severe Leg Pain During Long Rides. Taking Treatment For S1 An L5 Injuries And Neuropathic Pain. Concerned

Do you mean severe leg pain when you drive the car? If so it may be because of tight accelerator / brakes. Service them to suit to your needs. This is so because in order to use them you need to flex the plantar muscles (in the foot) which are innervated by tibial nerve which is a peripheral nerve from S1 spinal segment. The leg pain increases on constant use.
Second you should not sit for longer durations at any time, ideally not more than 15 minutes. Sitting can increase the stress on the lower back by 40%.
You should take pain modulators like Gabapentin, Mecobalamin from the treating physician.
Physiotherapy ( pain relieving exericses) and practice of yoga especially few asanas (postures) is highly recommended in consulting the doctor.
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