Question: Well, it's Saturday so I can't contact my APN Psych doc about a medication question. I'm almost 61 and have been a psych patient for many years battling PD/Dep/OCD Anxiety - post Grave's disease in 1977 but symptoms have been with me since childhood. Anyway, I've been on a lot of different meds since the early 80's. Zoloft and Xanax (PRN) worked for about 10 years, then Effexor XR worked for about 13 yrs then I got sick with a stomach flu and everything stopped and I started having bad PD again along with horrible withdrawal from the Effexor. I then tried Pristiq (not much help) and Lexapro (not much help) and then was on Tofranil (62mg/day divided into 3 doses) and low dose Ativan (1mg per day divided into 3 doses) for past 8 months which did help everything but the OCD which seem to get worse and developed into S-OCD - so I just made the change to Anafranil (50mg) yesterday. My doc said the switch between the two Tricyclics would be easy enough that no titration would be needed and that I could take a little more Ativan for anxiety if needed. So I took my last Tofranil (25mg) yesterday morning, skipped my usual half tablet at noon (because Anafranil only comes in capsules so can't be halved of course), picked up my new RX from the pharmacy and took the first 25mg dose of Anafranil last night. Didn't sleep much. I get very apprehensive and worry alot when starting new meds until I see how they make me feel (side-effects). I woke up this morning feeling panicky so I took my morning dose of Anafranil and 0.25mg of Ativan, then another 0.25mg of Ativan and 1pm. I'm doing better but I just need some reassurance that doing the switch of those meds like I did was ok....??