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Suggest Treatment For Acute Myeloid Leukemia

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Posted on Wed, 12 Nov 2014
Question: Please find here the Daily Report of confirmed AML Patient. But not yet started the medication. Please review the report
doctor
Answered by Dr. Meher Lakshmi Konatam (50 minutes later)
Brief Answer:
CBP doesnt give information on cure

Detailed Answer:
I wonder what you want from the CBP reports.
If diagnosis of Acute Myeloid Leukemia is confirmed, she needs to be started on chemotherapy at the earliest. There is no other option for treatment except chemotherapy. Even with chemotherapy, chances of remission with induction is 70% and there is 30% chance of disease being refractory to therapy. please understand that AML is a deadly disease.
If you do not want to take chemotherapy, she can be maintained on best supportive care for a few months. CBP daily is not the predictor of disease progression but clinical symptoms are more important. Diagnosis of AML itself means that it is advanced condition and there is nothing more to progress but clinical condition worsens with time. Best would be to start treatment at the earliest before she worsens
Above answer was peer-reviewed by : Dr. Shanthi.E
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Follow up: Dr. Meher Lakshmi Konatam (46 minutes later)
What is the chances of Full recovery from AML
doctor
Answered by Dr. Meher Lakshmi Konatam (4 hours later)
Brief Answer:
Cure not possible

Detailed Answer:
Unfortunately AML is a disease with no cure. After induction approximately 70% chance of remission is present. After remission consolidation chemotherapy is offered. Inspite of all these disease relapses in 1 to 2 years. In AML, relapse is a rule rather than a chance. Even allogenic transplantation doesnt offer complete cure. It is hard to hear all these, but these are facts and no one can offer complete cure
Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
doctor
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Follow up: Dr. Meher Lakshmi Konatam (15 hours later)
Hi, I have provided some attachments. Please review them.
doctor
Answered by Dr. Meher Lakshmi Konatam (2 hours later)
Brief Answer:
Repeat BMA and flow cytometry

Detailed Answer:
The bone marrow report says it is monocytic leukemia. Since it has been a month since the diagnosis and she is not yet started on therapy, I suggest BMA to be repeated again and preserve sample for flow cytometry. If marrow is ambiguous, flow can be done.

I feel Bone marrow aspiration to be repeated. Biopsy not necessary
Above answer was peer-reviewed by : Dr. Ashwin Bhandari
doctor
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Follow up: Dr. Meher Lakshmi Konatam (18 minutes later)
Attached here the Flow Cytometry report. Kindly review it.
doctor
Answered by Dr. Meher Lakshmi Konatam (5 minutes later)
Brief Answer:
flow report is classical of AML

Detailed Answer:
the flow report you sent is classical of AML. There is no ambiguity in this report.
Since her platelet count is still maintaining I feel it is best to start treatment at the earliest. As time passes by, platelet count falls and need for platelet support increases. Results are bad if treated is started when the patient is sick. So understand the situation and take decision early
Note: For further queries related to kidney problems Click here.

Above answer was peer-reviewed by : Dr. Ashwin Bhandari
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Answered by
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Dr. Meher Lakshmi Konatam

Oncologist

Practicing since :2001

Answered : 292 Questions

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Suggest Treatment For Acute Myeloid Leukemia

Brief Answer: CBP doesnt give information on cure Detailed Answer: I wonder what you want from the CBP reports. If diagnosis of Acute Myeloid Leukemia is confirmed, she needs to be started on chemotherapy at the earliest. There is no other option for treatment except chemotherapy. Even with chemotherapy, chances of remission with induction is 70% and there is 30% chance of disease being refractory to therapy. please understand that AML is a deadly disease. If you do not want to take chemotherapy, she can be maintained on best supportive care for a few months. CBP daily is not the predictor of disease progression but clinical symptoms are more important. Diagnosis of AML itself means that it is advanced condition and there is nothing more to progress but clinical condition worsens with time. Best would be to start treatment at the earliest before she worsens