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Suggest Treatment For Pyridoxine Dependant Epilepsy
Question: For patient with PDE(pyridoxine dependant epilepsy) aged 30 years weighing 70 Kgs what is appropriate dosage of pyridoxine hydrochloride( say Benadon)?
Brief Answer:
About 50-100 mg daily pyridoxine
Detailed Answer:
Hello XXXXXXX
I have gone through your question and understand your concerns.
In pyridoxine dependent epilpesy usual dosing is about 50-100 mg . wide variation of dosage are reported but it is best to take as little as possible to control the seizures.
About 50 mg -100 mg will be adequate in your case.
Higher doses have risk of pyridoxine associated neuropathy.
You can read more about treatment at
http://www.ncbi.nlm.nih.gov/books/NBK1486/
http://www.indianpediatrics.net/july2003/july-633-638.htm
Hope you found the answer helpful.
regards
Dr Neeraj Kumar
neurologist
About 50-100 mg daily pyridoxine
Detailed Answer:
Hello XXXXXXX
I have gone through your question and understand your concerns.
In pyridoxine dependent epilpesy usual dosing is about 50-100 mg . wide variation of dosage are reported but it is best to take as little as possible to control the seizures.
About 50 mg -100 mg will be adequate in your case.
Higher doses have risk of pyridoxine associated neuropathy.
You can read more about treatment at
http://www.ncbi.nlm.nih.gov/books/NBK1486/
http://www.indianpediatrics.net/july2003/july-633-638.htm
Hope you found the answer helpful.
regards
Dr Neeraj Kumar
neurologist
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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