Brief Answer: You apparently have a concurrent mixed infection Detailed Answer: Hi there, Thanks for your query. From the information provided, it is apparently a case of sexually transmitted disease, due to chlamydia, yeast and/or gonococci, causing oral + genital infection. Oral infection spreads by oral sex/kissing an infected partner. The reasons for non-response to the medicines include, concurrent treatment of all infections; resistance to the drugs taken; or, inadequate duration/dose of drug. You should therefore treat yourself with both : gonococcal + chlamydial + yeast infection concurrently. I will therefore recommend that you take Azithromycin 1 gm (single dose) on day 1; followed by 500mg daily for one week; Doxycycline 100mg twice a day for one week; and, Tab Fluconazole 150mg once a day for 3 weeks. In addition, there is also a strong possibility of Herpes infection. Get yourself investigated for this viral infection, which- incidentally- is incurable, and tends to flare up repeatedly in future. Consult your doctor and apprise him of my opinion. I am certain that he agrees with my opinion and clinical acumen; order required tests, and- based on the reports- will arrive at a certain diagnosis and prescribe suitable treatment as advised. Hope I have addressed to your concerns to your complete satisfaction and you find my response helpful and informative. I will be happy to answer further queries, if any. Fond regards and have a nice day, Dr. Rakesh Karanwal

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