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What Causes Altered AST And ALT Levels?

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Posted on Thu, 21 Aug 2014
Question: My AST is 109 and ALT 126. ALP is 86 and bilirubin is 1.0. I was in normal limits for AST and ALT last year. Should I be concerned?
Should I be concerned with these results?
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Answered by Dr. Ivo Ditah (2 hours later)
Brief Answer:
These results need further attention!

Detailed Answer:
Hi and thank you so much for this query.

I am so sorry to hear about these increased liver markers. Clearly, they are out of the normal ranges and further measures through a complete clinical examination and laboratory investigations should be undertaken to identify the cause of this abnormality and addressed appropriately. They suggest a liver pathology.

For this, I will suggest that you follow up with a gastroenterologist. For now, reduce your alcohol consumption, avoid medications like Tylenol when not really needed, etc.

In all, you have got reasons to be concerned. Talk to your doctor and get a possible referral to see a gastroeneterologist to pinpoint the cause of these abnormal results and address accordingly.

I hope this helps. I wish you well. Thanks for trusting us with your health question this day and feel free to ask for more information and clarifications if need be.
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Ivo Ditah

Internal Medicine Specialist

Practicing since :2002

Answered : 3984 Questions

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What Causes Altered AST And ALT Levels?

Brief Answer: These results need further attention! Detailed Answer: Hi and thank you so much for this query. I am so sorry to hear about these increased liver markers. Clearly, they are out of the normal ranges and further measures through a complete clinical examination and laboratory investigations should be undertaken to identify the cause of this abnormality and addressed appropriately. They suggest a liver pathology. For this, I will suggest that you follow up with a gastroenterologist. For now, reduce your alcohol consumption, avoid medications like Tylenol when not really needed, etc. In all, you have got reasons to be concerned. Talk to your doctor and get a possible referral to see a gastroeneterologist to pinpoint the cause of these abnormal results and address accordingly. I hope this helps. I wish you well. Thanks for trusting us with your health question this day and feel free to ask for more information and clarifications if need be.