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What Causes Elevated GGT And ALT Levels In Blood While On TPN?

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Posted on Fri, 22 Jan 2016
Question: My son who is TPN dependent has elevated GGT & ALT levels. He recently had C-Diff. Is there a correlation?
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Answered by Dr. Archana Verma (2 hours later)
Brief Answer:
It is suggestive of liver dysfunction

Detailed Answer:
Hi
I understand your concerns but don't worry.

The raised ALT and GGT are suggestive of liver dysfunction which is most likely due to TPN (total parenteral nutrition) in your child. It's a well known side effect of TPN. The clinical condition and extent of liver dysfunction determines the line of management. I would recommend you to go with your doctor's advice of ultrasound abdomen.

Clostridium difficile infection doesn't have such associated complications.

Hopefully it will be of help.
Take care
Note: For further queries related to your child health, Talk to a Pediatrician. Click here to Book a Consultation.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Archana Verma

Pediatrician

Practicing since :2006

Answered : 1129 Questions

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What Causes Elevated GGT And ALT Levels In Blood While On TPN?

Brief Answer: It is suggestive of liver dysfunction Detailed Answer: Hi I understand your concerns but don't worry. The raised ALT and GGT are suggestive of liver dysfunction which is most likely due to TPN (total parenteral nutrition) in your child. It's a well known side effect of TPN. The clinical condition and extent of liver dysfunction determines the line of management. I would recommend you to go with your doctor's advice of ultrasound abdomen. Clostridium difficile infection doesn't have such associated complications. Hopefully it will be of help. Take care