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What Causes Elevated IgE And Hives?

Posted on Tue, 29 Apr 2014

Question: I had my patch testing and I want to know how you think of the result by the photo I have. How can I paste photo here?

Answered by Dr. Dr.Raju.A.T (30 hours later)

Brief Answer: Reactive Detailed Answer: Hi, Thanks for your query. Sorry for the delay in my response. With elevated IgE and hives to many regular allergens indicate you have Atopy, a hereditary predisposition for hypersensitivity. There will be a generalized or localized reaction to all known allergens here, hence the diagnosis is easy and is also supported by elevated IgE. You patch test in the image shows positive dermatitis reaction. This is a presentation in moderate severity of Atopy. It is difficult to treat people responding to a single allergen, where the treatment is avoiding the allergen. Since its a generalized overactive response system it can be suppressed with medications like mast cell stabilizers and leukotriene antagonist to some extent. The definitive treatment in case of recurrent and worsening condition is by Coirticosteroids. Hope, I answered your query. Wish you good health. Regards,

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr.Raju.A.T (3 hours later)

Thank you, Dr. XXXXXXX I went to my dermatologist today, and my reacted red spot was Thimerosal which is very common in non-soap cleaners, Antisptic sprays, topical medications, eye makeup, and also in skin prick test agents. It is confusing but my Dermatologist said, he doesn't consider it as a positive result since Thimerosal is commonly found old time vaccine, I am 50, so i got vaccination long time ago, but the childhood vaccine would cause False Positive reaction on my back like that? I had skin prick test in mid February this year and found environmental allergy i mentioned in my past inquiry. Is it possible to make my idiopathic urticaria occasioonally after the prick test with the sinsitivity to Thimerosal if i was allergic to it? I just read online that Thimerosal makes false-Positive reaction if i was sensitive to Mercury. I am Japanese, i have eaten a lot of fish by now, I don't recognize sensitivity to food contained possible Mercury. If I was not sensitive to Mercury, then the Thimerosal reaction on my patch testing should be reevaluated with follow up testing? i agree with you Dr. XXXXXXX I see it as positive reaction, so i take your opinion more pursasive than my Dermatologist opinion. I am still waiting for my skin Biopsy resut. My Dermatologist is testing Eosinophil in my skin to see if I have solid allergy and makes systemic urticaria. I am still seraching for more of possible allergen so your opinion about Thimerosal would be greatly appreciated. Atopic allergy to multiple allergen in the air or chemicals would be harder to treat? I am scared but i want some more knowlege with your help. Thank you.

Answered by Dr. Dr.Raju.A.T (39 minutes later)

Brief Answer: Past vaccine cross reaction is least possibility Detailed Answer: Hi, Thanks for writing back. I do not agree with your dermatologist. Well, there can be memory of such an old vaccine related allergy but it would surely present with serious hypersensitivity anaphylaxis after second exposure to thimerosal. Reactivity to mercury should have been experienced as you doubt, if this reaction was a thimerosal specific. This, as I believe is a non allergen specific allergic reaction, systemic urticaria for sure. Get the Biopsy result, it could add very good weight to your work up. Wish you good health. Regards,

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr.Raju.A.T (13 minutes later)

Thank you very much for your opinion Dr. XXXXXXX I have more confident to look into my Biopsy result and future recovery with my condition. You helped me a lot and i cannot say thank you enough for your time to answer me.

Answered by Dr. Dr.Raju.A.T (16 hours later)

Brief Answer: You are welcome Detailed Answer: Thanks for using this service. Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr.Raju.A.T (2 hours later)

I got biopsy reslut back, but only XXXXXXX the phone, the nurse only said it was a hive no other comments were back other than that today. I aksed her to send the copy of actual lab result. I will come back if i have a question from the alab result.

Answered by Dr. Dr.Raju.A.T (1 hour later)

Brief Answer: Sure Detailed Answer: Will be waiting Regards,

Note: For further information on diet changes to reduce allergy symptoms or to boost your immunity, Ask here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar