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What Causes High Eosinophil Count And Low GFR?

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Posted on Thu, 25 Jun 2015
Question: I have a high eosinophil count and it has gone from 12 to 13 in the past 2 years. My GFR is also low being 48. I have a history of cervical adenocarcinoma with radical hysterectomy in 2006.
Should I be concerned.......
doctor
Answered by Dr. Michelle Gibson James (23 minutes later)
Brief Answer:
the low GFR is concerning

Detailed Answer:
HI, thanks for using healthcare magic

Eosinophils are one of the type of white blood cells found in the body.

The white blood cells respond to inflammation and/or infection.

Eosinophils tend to respond to allergic reactions, asthma and in some parasite infections.
If a person has a history of sinuses, rhinitis or any allergies, the eosinophils would increase.


The change from 12 to 13 is not significant, this would not be considered to be any change at all because it is very minor.

Your GFR however is low and indicates significant kidney disease.

To prevent any further deterioration , you and your doctor would need to make sure that any factor that can affect the kidney is controlled.

This means blood pressure, blood sugar, checking and controlling any underlying kidney disease, eliminating any medications that can affect the kidney

Supplements may be needed.

I hope this helps, feel free to ask any other questions
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Michelle Gibson James (4 minutes later)
I know the change isnt much in eosinophil count, but because it has been high for 2 years I wondered if it was a concern. My gfr last year was 50 so that has also gotten slightly worse. I left a message for my primary MD and she wasnt concerned. Should I get a second opinion from nephrologist?
doctor
Answered by Dr. Michelle Gibson James (50 minutes later)
Brief Answer:
eosinophils normally increased due to allergies in most persons

Detailed Answer:
HI

Because eosinophils are usually reflective of allergies/inflammation in most persons when increased, it is not likely a concern.
As mentioned, they are also high in parasitic infection but if you had an infection the white cell count would be high and it is normal in the results.

The GFR has worsened slighty, it still places you in the stage 3 of kidney disease.

If you have not seen a nephrologist at any point for your kidney function then you should consider seeing one at least for an evaluation.

If you have seen one, because the change is from 50 to 48 then you need to continue controlling your risk factors and monitor

Please feel free to ask any other questions
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 16808 Questions

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What Causes High Eosinophil Count And Low GFR?

Brief Answer: the low GFR is concerning Detailed Answer: HI, thanks for using healthcare magic Eosinophils are one of the type of white blood cells found in the body. The white blood cells respond to inflammation and/or infection. Eosinophils tend to respond to allergic reactions, asthma and in some parasite infections. If a person has a history of sinuses, rhinitis or any allergies, the eosinophils would increase. The change from 12 to 13 is not significant, this would not be considered to be any change at all because it is very minor. Your GFR however is low and indicates significant kidney disease. To prevent any further deterioration , you and your doctor would need to make sure that any factor that can affect the kidney is controlled. This means blood pressure, blood sugar, checking and controlling any underlying kidney disease, eliminating any medications that can affect the kidney Supplements may be needed. I hope this helps, feel free to ask any other questions