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What Causes Low Cd4/ Cd8 Ratio?

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Posted on Thu, 13 Nov 2014
Question: What is cause of low cd4/cd8 ratio
cd4 -480
cd8-756
cd4\cd8-0
.63
tested for HIV and it is negative after four months .please advise I am completely healthy.please help
doctor
Answered by Dr. Arun (54 minutes later)
Brief Answer:
Retesting of CD4 and CD8, kindly attach HIV report

Detailed Answer:
Hello XXXX,
I understand your concern. I am Dr Arun Tank, infectious diseases specialist answering your query.

- Normal CD 4 count is 500 to 1200 and CD 8 count is 150 to 1000 cells/mm³, normal CD 4/8 ratio is 1 to 2.

- Your ratio and CD4 count is less but HIV test is Non Reactive after 4 month.

- This condition won't make you HIV positive. It is necessary to retest for CD4 & 8 ratio. Some times normal variation in CD 4 and 8 is the reason for the variation in the ratio. I advice you to retest after a month.

- Kindly provide me the test report of HIV to help you more.

I will be happy to answer your future query.
Kindly come up with query.
Thank you,
Dr Arun Tank,
Infectious diseases specialist.
Above answer was peer-reviewed by : Dr. Ashwin Bhandari
doctor
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Follow up: Dr. Arun (26 minutes later)
I have cd4/cd8 cell test 9th October
cd4 -502
cd8-885
cd4/cd8 -0.56

on 10th october different lab
cd4 -480
cd8-756
cd4\cd8-0
.63

I have HIV fourth generation test at metropolis lab XXXXXXX and result non reactive 0.18
doctor
Answered by Dr. Arun (32 minutes later)
Brief Answer:
No HIV, Retesting for CD4/8 is required..

Detailed Answer:
Hello XXXX,

- You had undergone CD4/8 testing on second consecutive day. You at least have to give a period of 15 to 20 days for retesting.

- As you had taken fourth generation ELISA testing after four month, if the result confirms negative, there is nothing to worry about HIV.

Kindly come up for further clarification.

Thank you,
Dr. Arun Tank
Infectious Disease Specialist.
If your query has been resolved kindly rate me as a five star and close the answer.

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Above answer was peer-reviewed by : Dr. Bhagyalaxmi Nalaparaju
doctor
Answered by
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Dr. Arun

Infectious Diseases Specialist

Practicing since :2008

Answered : 2434 Questions

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What Causes Low Cd4/ Cd8 Ratio?

Brief Answer: Retesting of CD4 and CD8, kindly attach HIV report Detailed Answer: Hello XXXX, I understand your concern. I am Dr Arun Tank, infectious diseases specialist answering your query. - Normal CD 4 count is 500 to 1200 and CD 8 count is 150 to 1000 cells/mm³, normal CD 4/8 ratio is 1 to 2. - Your ratio and CD4 count is less but HIV test is Non Reactive after 4 month. - This condition won't make you HIV positive. It is necessary to retest for CD4 & 8 ratio. Some times normal variation in CD 4 and 8 is the reason for the variation in the ratio. I advice you to retest after a month. - Kindly provide me the test report of HIV to help you more. I will be happy to answer your future query. Kindly come up with query. Thank you, Dr Arun Tank, Infectious diseases specialist.