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What Causes Low Vitamin D Levels And High PH Levels?
Question: Hello, my dad is being seen by an endocrinologist. He is 61 years old and over all healthy. Recently he went to the doctor and they told him that his Vitamin D levels were off the charts high, his PH levels are high, and he has hypothyroidism. They were concern that he might have a blood disorder - leukemia or lymphomic cancer - even though his only symptom is fatigue? I need someone to explain to me the jump of conclusions to having cancer when they have no concrete evidence. He is getting a smear done tomorrow. Please give me a detail answered - no fluff, want the biology of it all. Thank you!
Brief Answer:
Detail Follows.
Detailed Answer:
Welcome To HCM. I am Dr Anshul Varshney.
I understand your concern.
See Low Vitamin D levels are very common. Nothing to worry for that. This can be replenished by supplement.
Your doctor must have found something that had given idea of lymphoma.
Might be his high calcium levels, atypical cells in blood, chest Xray lesion or apparent lymph nodes.
Hypothyroidism and low Vitamin D don't at all indicate presence of Lymphoma or any malignancy.
However I need more details regarding the PH levels you are mentioning. Is that blood PH or Urine PH?
Describe me his symptoms and if possible attach his blood reports.
Stay Healthy.
Detail Follows.
Detailed Answer:
Welcome To HCM. I am Dr Anshul Varshney.
I understand your concern.
See Low Vitamin D levels are very common. Nothing to worry for that. This can be replenished by supplement.
Your doctor must have found something that had given idea of lymphoma.
Might be his high calcium levels, atypical cells in blood, chest Xray lesion or apparent lymph nodes.
Hypothyroidism and low Vitamin D don't at all indicate presence of Lymphoma or any malignancy.
However I need more details regarding the PH levels you are mentioning. Is that blood PH or Urine PH?
Describe me his symptoms and if possible attach his blood reports.
Stay Healthy.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Hello
You must mis-understand he has "high vitamin d" levels not low. Also, I was wrong about the ph level, he has "low phosphorous levels". They ordered some kind of test called 125 or something where his numbers needed to be between 11-74 and he was 149. He has had a swollen lymph node for 2 years, it went down a little when he had diverticulitis (sorry about spelling) on the antibiotics. However, it never went down fully. I'm just trying to make sense of this all. I have a degree in biology so I would appreciate more explanation on how this works. Thank you!
You must mis-understand he has "high vitamin d" levels not low. Also, I was wrong about the ph level, he has "low phosphorous levels". They ordered some kind of test called 125 or something where his numbers needed to be between 11-74 and he was 149. He has had a swollen lymph node for 2 years, it went down a little when he had diverticulitis (sorry about spelling) on the antibiotics. However, it never went down fully. I'm just trying to make sense of this all. I have a degree in biology so I would appreciate more explanation on how this works. Thank you!
Brief Answer:
Detail Follows.
Detailed Answer:
Dear Friend.
Now this becomes worrisome.
High levels of Vitamin D (the test must be 1,25 hydroxyvitamin D3 levels) is associated with hypercalcemia and low PTH (Parathormone) which can subsequently reduce the phosphorus levels.
This high level of Vitamin D can be found in various conditions like Drug toxicity , Sarcoidosis, but yes sorry to say but Lymphoma is a possibility.
Now a Lymphoma present any where in the body excreted Vitamin D which subsequently orders Parathyroid glands and Kidneys to produce more and more calcium which in turn reduces phosphorus levels.
Just increase Vitamin D level is not a problem directly. Problem is to find why it is rising. And most commonly it rises because of Lymphoma secreting it.
I tried my best you explain you and I am hopeful that you must have understood being a biology degree holder.
If you have any further query please ask me.
Detail Follows.
Detailed Answer:
Dear Friend.
Now this becomes worrisome.
High levels of Vitamin D (the test must be 1,25 hydroxyvitamin D3 levels) is associated with hypercalcemia and low PTH (Parathormone) which can subsequently reduce the phosphorus levels.
This high level of Vitamin D can be found in various conditions like Drug toxicity , Sarcoidosis, but yes sorry to say but Lymphoma is a possibility.
Now a Lymphoma present any where in the body excreted Vitamin D which subsequently orders Parathyroid glands and Kidneys to produce more and more calcium which in turn reduces phosphorus levels.
Just increase Vitamin D level is not a problem directly. Problem is to find why it is rising. And most commonly it rises because of Lymphoma secreting it.
I tried my best you explain you and I am hopeful that you must have understood being a biology degree holder.
If you have any further query please ask me.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
One more question then, high about if he takes high blood pressure medicine could that cause this? Thanks!
Brief Answer:
Detail Follows.
Detailed Answer:
Dear Friend.
I would like to know which all BP medications and other medications he is taking before I can comment on that.
Detail Follows.
Detailed Answer:
Dear Friend.
I would like to know which all BP medications and other medications he is taking before I can comment on that.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
He is taking one called lip something like that. Um for other medications thats pretty much it. He is healthy, and doesn't really have anything else wrong...
Brief Answer:
Detail Follows.
Detailed Answer:
Dear Friend.
Why don't you check and get back to me with his medicine details. The lip can be Atorlip or Lisinopril.
It would be very inappropriate comment on the medicine and such serious condition.
So let's be sure by discussing sure things.
Check his medications and write to me again.
However in any case he would require Bone marrow , CT , PET scan to find any evidence of Lymphoma.
Detail Follows.
Detailed Answer:
Dear Friend.
Why don't you check and get back to me with his medicine details. The lip can be Atorlip or Lisinopril.
It would be very inappropriate comment on the medicine and such serious condition.
So let's be sure by discussing sure things.
Check his medications and write to me again.
However in any case he would require Bone marrow , CT , PET scan to find any evidence of Lymphoma.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
It is Lisinopril that is the right one. And that helps so the blood smear can that see the cancerous cells or is that just for the leukemia?
Brief Answer:
Detail Follows.
Detailed Answer:
Dear Friend.
Lisinopril is unlikely to cause such hypervitaminosis D.
Blood smear helps in detection of leukemia cells.
But I suppose they must have planned bone marrow followed by scanning because that is the standard of investigations.
Stay Healthy.
Detail Follows.
Detailed Answer:
Dear Friend.
Lisinopril is unlikely to cause such hypervitaminosis D.
Blood smear helps in detection of leukemia cells.
But I suppose they must have planned bone marrow followed by scanning because that is the standard of investigations.
Stay Healthy.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
He is seeing an endocrinologist right now so I think that is where he is sending him next. Guess I will just keep praying that the Lord has mercy on my Dad. Thank you for your help! I realize how serious this is and now I can be somewhat prepared on the following up coming procedures and make arrangements to begin to go back and see him. Thank you!
Brief Answer:
Good Luck.
Detailed Answer:
Dear Friend.
Don't worry. Things will be fine with God's grace.
Wish him long happy and Healthy life
Revert back with his updates.
If you have any further query please ask me else close the discussion and rate it.
Stay Healthy.
Good Luck.
Detailed Answer:
Dear Friend.
Don't worry. Things will be fine with God's grace.
Wish him long happy and Healthy life
Revert back with his updates.
If you have any further query please ask me else close the discussion and rate it.
Stay Healthy.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Hello
So I just find out that my dad also has large pallets with the high vitamin D and low phosphorous....his lymphocytes were on the higher end but still in the normal range - could this still be cancer or some kind of disorder?
So I just find out that my dad also has large pallets with the high vitamin D and low phosphorous....his lymphocytes were on the higher end but still in the normal range - could this still be cancer or some kind of disorder?
Brief Answer:
MRI and PET scan
Detailed Answer:
Dear Friend.
Welcome back.
I am sorry but I couldn't understand what you meant by large pallets. Please explain.
As far as lymphocytes count are concerned even if they are on the higher side, any cancer can't be estimated by just this count.
He would certainly require MRI and PET scan to be sure.
I would like to have a look on his all the reports.
If you have them, attach and send to me.
Stay Healthy
MRI and PET scan
Detailed Answer:
Dear Friend.
Welcome back.
I am sorry but I couldn't understand what you meant by large pallets. Please explain.
As far as lymphocytes count are concerned even if they are on the higher side, any cancer can't be estimated by just this count.
He would certainly require MRI and PET scan to be sure.
I would like to have a look on his all the reports.
If you have them, attach and send to me.
Stay Healthy
Above answer was peer-reviewed by :
Dr. Raju A.T
The Large Pallets they find in his blood smear - they said "Rare Large Pallets" in the blood.....I guess there was enough where they were extremely concerned. That is all I know.
Brief Answer:
It must be Large Platelets.
Detailed Answer:
Dear Friend.
I suppose were talking about large platelets.
You might have wrongly heard.
If they were there, it is a matter of concern. Large platelets and even increase no. of Platelets in blood smear indicate towards something wrong.
I suppose his bone marrow must be done by now.
Let the report come.
If possible attach all the reports.
Stay Healthy.
It must be Large Platelets.
Detailed Answer:
Dear Friend.
I suppose were talking about large platelets.
You might have wrongly heard.
If they were there, it is a matter of concern. Large platelets and even increase no. of Platelets in blood smear indicate towards something wrong.
I suppose his bone marrow must be done by now.
Let the report come.
If possible attach all the reports.
Stay Healthy.
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now
Above answer was peer-reviewed by :
Dr. Raju A.T
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