Question: My wife is taking Metoprolol 25 MG after having 4 stents placed 1 and half years ago. She is experiencing memory loss, and confusion . She is 81 years old. She has never had high blood pressure. Why does she need to take this beta-blocker to reduce blood pressure? Is this medication along with Clopidogrel, Losartan and Atorvastatin can seriously decrease her cognitive ability, confusion and halucination?? Sorry not decrease, INCREASE !!

Dear Dr. Zografakis, I understand your reply and kind of agree with that. You cannot provide else then the "regular understanding" of a medication. I like better when you mentioning that Metoprolol can be blamed more than the other medication. Pls allow me to make some comments or more precisely ask some further questions: It is suggested and obviously I like to believe that our problem is caused by deteriorated vascular problem than Alzheimer. (Tests, MRI etc) Here are my questions; 1. Although metoprolol is a necessary medication in those cases and it is a well known and good medicine, but there are better new medicines like Bisoprolol (Concor cor i.e. 1.25 MG) that are causing much less negative side-effects and better control blood pressure and arrythmias. What would you be your view on changing the medication to this?? 2. It is also mentioned in the literature that Calcium-channel blockers (i.e. Verpamil) can have less side-effect and what is more it is better tolarated by elderly persons. 3. It is well know that Atorvastatin is replaced by Rosuvastatin that can be administered in smaller dose and expected to create much less negative side-effect. Can atorvastatin be replaced by rosuvastatin, with careful and continuous monitoring?
Since , it is believed that the mentioned changes in the patient's mental and cognitive and health herbivore most probably caused by vascular deterioration, in this case the blood circulation and oxygen transfer in the brain and heart would be required to be increased by well known medication or supplements that cause no or very little negative side-effect? It is known, that for example the Cavinton forte ( the alkaloid of vinca minor, i.e.Vinpocetine) can be a very effective supplement/medication. The other very well praised medicine the Trental (pentoxifyllin in 400 or 600 MG ) cannot be or should not be prescribed for the patients taking metoprolol or even bisoprolol ?? It is not a vasodilator, but positiv way effects on the red blood cells, that after treating them with pentoxifyllin they regain their ability to deform , and consequently they become able to move through tighter and more ridged or twisting/winding blood vessels and carry the oxygen to the brain cells. The effect of the Cavinton forte and Trental can further be enhanced by Neuromultivitamine that contains the necessary B vitamin in larger dose that are vital for the brain's nerve cells. Such vitamin like the Thiamin in 10MG suggested to be quite effective.
Dear Doctor! I have many questions for you and I hope that you will be kind enough to provide me the necessary help and information to evaluate the value and necessity of the mentioned new and old medications . Your research and literature review would be a great help and I am extremely shameful for asking so many questions and information, but probably it is needless to say how important this can be for us and perhaps many more elderly patients. Thank you. Sincerely, XXXX PS: I am not a medical doctor or physician, and all what I am communicating to you is learned from the appropriate sources, internet and from some of my foreign physicians. The state and information of the US health professional is obviously most important for establishing the best locally available and approved treatment system.