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What Causes Severe Depression, Memory Loss And Weight Loss While On Zonegran?

Posted on Mon, 30 Nov 2015

Question: i am 26 year old female 5/3 and 114 pounds.... I have been diagonosed with epilepsy in the past two months and was started on zonegran....prior to this i was diagnosed with PCOS and fybromyalgia bordering lupus.... I have been experiencing severe depression, memory loss, weight loss, horrible rashes and pain. Recently I found bruises covering my legs and my urine and stool had blood. the er results showed out of normal range levels for Hyaline casts, platelet levels, squamous epithileal, leukoycyte, white blood cells and protein. The past two days severe pain below my left ribs and i cannot drink water because it tastes bitter and terrible... what is happening to me?

Answered by Dr. Neeraj Kumar (2 hours later)

Brief Answer:
Seems to be drug related side effect

Detailed Answer:
Hello,
I have gone through your question and understand your concerns.
The symptoms enumerated by you may be side effects of zonisamide you are taking for seizures.
It will be better to consult your neurologist and get changed your drug. Levetiracetam is a better option for generalized idiopathic seizure.
What was your Mri and eeg reports.
Any family history?
Types of seizures?
Upload any investigation or reports if available.
Hope you found the answer helpful.
Do get back to me for further queries.
Regards
Dr Neeraj Kumar
Neurologist

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Neeraj Kumar (47 minutes later)

my MRI and eeg has been clean- I go every year since my first seizure 3 years ago ..... No seizure history in my family .........My biggest problem has been that I have not been able to get in touch with my neurologist since and she did not schedule me for a follow up till december 16th.....So i am totally clueless ..... What else could these symptoms and test results indicate an issue of?

Answered by Dr. Neeraj Kumar (1 hour later)

Brief Answer:
Other possibility may be Systemic lupus erythematosus (SLE)

Detailed Answer:
Hello,
Are you having seizure recurrences since first seizure ?
You should consult another neurologist who is available sooner or a physician who can evaluate and prescribe medications for seizures.
Other disease possibilities with such symptom complex may be Systemic lupus erythematosus (SLE) with skin lesions, neurological presentation and depression.
You need to get detailed examination and investigations.
For borderline lupus you can consult a immunologist for assessment and treatment accordingly.
Regards
Dr Neeraj Kumar
neurologist

Above answer was peer-reviewed by : Dr. Prasad