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What Do The Following Test Results Suggest?

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Posted on Wed, 29 Jun 2016
Question: F UREA NITROGEN (BUN) 18 7-25 (mg/dL) NL1
F CREATININE 1.00 0.70-1.33 (mg/dL) NL1
- For patients >49 years of age, the reference limit
- for Creatinine is approximately 13% higher for people
- identified as African-American.


F eGFR NON-AFR. XXXXXXX 85 > OR = 60 (mL/min/1.73m2) NL1
F eGFR XXXXXXX XXXXXXX 98 > OR = 60 (mL/min/1.73m2) NL1
F BUN/CREATININE RATIO NOT APPLICABLE 6-22 ((calc)) NL1
F SODIUM 144 135-146 (mmol/L) NL1
F POTASSIUM 4.6 3.5-5.3 (mmol/L) NL1
F CHLORIDE 107 98-110 (mmol/L) NL1
F CARBON DIOXIDE 26 19-30 (mmol/L) NL1
F CALCIUM 9.4 8.6-10.3 (mg/dL) NL1
F PROTEIN, TOTAL 6.6 6.1-8.1 (g/dL) NL1
F ALBUMIN 4.3 3.6-5.1 (g/dL) NL1
F GLOBULIN 2.3 1.9-3.7 (g/dL (calc)) NL1
F ALBUMIN/GLOBULIN RATIO 1.9 1.0-2.5 ((calc)) NL1
F BILIRUBIN, TOTAL 0.6 0.2-1.2 (mg/dL) NL1
F ALKALINE PHOSPHATASE 52 40-115 (U/L) NL1
F AST 47 H 10-35 (U/L) NL1
F ALT 65 H 9-46 (U/L) NL1
Blood test was done May 2nd 2016
how bad is the ast and alt ?
I am a daily drinker, I feel great.


I also should add I have cut back drinking and am on a low fat low carb diet
and lost 6 pounds since
doctor
Answered by Dr. Panagiotis Zografakis (3 hours later)
Brief Answer:
not too bad...

Detailed Answer:
Hello,

The only 'bad' results are the transaminases values. They're not too bad though. Drinking or being overweight (or obese) may cause such elevations. A liver ultrasound scan may detect fat deposition on the liver (fatty liver). I agree with repeat testing. I would have added gamma-GT which is useful to evaluate the effect of alcohol in the liver (heavy drinkers have increased gamma-GT).

If the ultrasound scan does not detect fatty liver then further testing might be required. Antinuclear antibodies and hepatitis serological testing would be the first tests to do in that case.

Loosing weight (if you're overweight) and cutting back on drinking are good decisions for your liver.

I hope it helps! Please contact me again, if you'd like more information or any clarification.

Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Panagiotis Zografakis (3 hours later)
Doctor suspects start of fatty liver but will retest...basically cut what your drinking now I half exercise lose weight and I should be fine..m I ate fatty foods all winter drank more than usual. ..and did not got to the gym as I usually do. ..gained 15 pounds could explain the situation. .also went to a race party day before blood was drawn and drank. Would that affect them ?
doctor
Answered by Dr. Panagiotis Zografakis (6 minutes later)
Brief Answer:
drinking may affect the tests but not always

Detailed Answer:
Fatty liver sounds like a possible cause of transaminases elevation. Drinking may affect the tests but this is not always the case. Weight gain builds a case for fatty liver but the ultrasound scan should confirm it (and also exclude other causes, which could be visible on the scan).

Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Panagiotis Zografakis (6 minutes later)
So cutting back exercise losing weight should resolve it ?
doctor
Answered by Dr. Panagiotis Zografakis (5 minutes later)
Brief Answer:
stopping alcohol and weight gain would help

Detailed Answer:
Cutting back exercise won't help. Actually exercise will help with weight loss.

Weight loss and abstinence from alcohol will help. Resolving it may take some time.


Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Panagiotis Zografakis (4 days later)
Hi Dr.

So you looked at my blood work and the other Liver numbers that are on this
particular test look normal correct ?
also is it likely to progress ? I have cut down drinking to one
or 2 per day and will start days with no drinking. I have lost 10 pounds this month.
I need to lose 15 more. I am exercising daily also. I am eating chicken
fish and veggies. as little fat and carbs as possible. so I am hoping things will look
better the end of XXXXXXX How concerned should I be until retested ? can I have one day a week to eat something for a meal as a reward ?

doctor
Answered by Dr. Panagiotis Zografakis (46 minutes later)
Brief Answer:
no concerns at this point

Detailed Answer:
Hi,

the transaminases are the only values worth to talk about. Progression depends on the cause and its management. If it's the alcohol or fatty liver then stopping the aggravating factor (the alcohol and excessive caloric intake) will help. Failure to do so, will result in worse numbers in the future. If this is not the cause then progression will depend on the actual disorder. For example autoimmune hepatitis may progress is left untreated. I've suggested tests to investigate it.

Loosing weight is very good, if you're overweight. And it's OK to eat something more once a week provided that you keep your calories down for the rest of the week.

At this point, there are no concerning results. The most likely cause is alcohol or obesity. If more data come out after investigation then this evaluation might have to be reconsidered.

Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Panagiotis Zografakis (11 minutes later)
would food and alcohol raise them slightly
with no fatty liver ? and thank you for your reply.
I have cut my drinking more than in half.
doctor
Answered by Dr. Panagiotis Zografakis (34 minutes later)
Brief Answer:
drinking too much might raise them

Detailed Answer:
Eating without being overweight or obese won't raise them. Alcohol may do so though. Drinking up to 1-2 glasses of wine per day (or any equivalent) is acceptable although at this point complete abstinence would be recommended to avoid confusing results.

Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3816 Questions

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What Do The Following Test Results Suggest?

Brief Answer: not too bad... Detailed Answer: Hello, The only 'bad' results are the transaminases values. They're not too bad though. Drinking or being overweight (or obese) may cause such elevations. A liver ultrasound scan may detect fat deposition on the liver (fatty liver). I agree with repeat testing. I would have added gamma-GT which is useful to evaluate the effect of alcohol in the liver (heavy drinkers have increased gamma-GT). If the ultrasound scan does not detect fatty liver then further testing might be required. Antinuclear antibodies and hepatitis serological testing would be the first tests to do in that case. Loosing weight (if you're overweight) and cutting back on drinking are good decisions for your liver. I hope it helps! Please contact me again, if you'd like more information or any clarification. Kind Regards!