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What Do These Hbeag, LFT And HBV DNA Quantitative Test Results Indicate?

Posted on Tue, 8 Sep 2015

Question: Hi, My friend had got tested hepatitis b recently and found that he is hbsag +ve, then conulted doctor,on suggestion of doctor got tested for hbeag ,lft and DNA quantitative viral count. below are the test results.
hepatits e antigen(Hbeag) SERUM - 0.37
Hepatits B viral(HBV DNA) Quantitative real time PCR 70 IU/ml
Liver Panel 1 LFT SERUM
AST(SGOT) 19 U/L
ALT(SGPT) 39 U/L
GGTP 41 U/L
Alkaline Phosphatase(ALP) 131 U/L
Bilirubin total 0.40 mg/dl
Bilirubin direct 0.09
biliburin indirect 0.31
total protein 7.50
albumin 4.40
A:G Ratio 1.42

Can you please tell me whether he needs to go for further test and what is state of his helath condition and is there any life threat for him?

Answered by Dr. Dr. BR Hudda (41 minutes later)

Brief Answer:
Please consider these guidelines

Detailed Answer:
Hello
I had gone through your question and reports very diligently and I will try to help you out in best possible way.
He is HBsAg positive but not in acute infective stage which means he is having hepatitis B infection.
Viral DNA Is comparatively very low, He can be labelled as chronic carrier
His liver function test(LFT) is within normal range.

There are chances of cirrhosis and liver cancer in life time with Hepatitis B infection
There are also chances of seroconversion if it is a recent infection
he has to undergo regular follow up testing for viral HBV DNA and liver function test

You need not to worry much about him chances of cirrhosis and liver cancer are there but not so common.
Please advise him to follow these guidelines
Get his wife and children tested for the same if he is married
Use condom during sex
Avoid sharing of tooth brush and razor

Hope this answers your question
please feel free to discuss further I will be happy to help you
Best regards

Above answer was peer-reviewed by : Dr. Raju A.T

Follow up: Dr. Dr. BR Hudda (9 hours later)

Thanks for the info. What is seroconversion. Beacuse we arr expecting that he might have got it recently and is there any chance that getting infection recently and can become chronic carrier? And in some blogs telling that even though all report looks fine, there may be chances of liver getting damaged? Does he need to go for ultrasound of liver?

Answered by Dr. Dr. BR Hudda (5 hours later)

Brief Answer:
Please consider these guidelines

Detailed Answer:
Hello
Welcome again
Seroconversion means adequate production of antibodies against hepatitis B virus by the body and that may clean up the virus and confer life long immunity against reinfection.

Chances of turning into a chronic carrier is always there with hepatitis infection so it can't be ruled out completely.
You need not to worry in case of acute infection antiviral drugs are available.

It's better to go for an ultrasound to find out any structural damage so you can go ahead for ultrasound or liver biopsy by an gastroenterologist.
He needs regular follow up and with LFT and viral load of hepatitis B virus.

It damages the liver in most of cases and may cause cirrhosis.
Hope this answers your question
wishing him good health
Regards

Above answer was peer-reviewed by : Dr. Vinay Bhardwaj

Follow up: Dr. Dr. BR Hudda (8 hours later)

Thanks.. one last question. Can you suggest diet details for him

Answered by Dr. Dr. BR Hudda (3 hours later)

Brief Answer:
Please consider these guidelines

Detailed Answer:
Hello
Welcome again
He should avoid hepatotoxic drugs and self medications, alcohol and smoking.

He should take lots of fresh fruits and green vegetables
He should avoid fatty fried and junk food
Multivitamin supplements are advisable

He should adopt healthy lifestyle otherwise nothing much to worry.
Hope this answers your question
Best wishes

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Above answer was peer-reviewed by : Dr. Neel Kudchadkar