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What Does My Urine Test Result Suggest?

Posted on Thu, 19 Mar 2015

Question: I have been tested with a 24 hr urine test,
Test gas return as such: beta globulin ' gamma globulin u,gamma globulin urine albumin u,alpha 1 alpha 2-ABNORMAL
PROTEIN 192-high
KAPPA QAUANT FREE LIGHT CHAINS 22.2 high
Free Lambda light chains, Ur 1.84 high
Kappa/Lambda free light chains ratio. 12.07 high

Suspicious band in gamma region with lambda specificity.

I am assuming we're looking for myeloma at this point. What is your thought on this test?8

Answered by Dr. Rakesh Madhyastha (2 hours later)

Brief Answer:
Multiple myeloma

Detailed Answer:
Hello

Thanks for the query

From the report you have furnished it does look like plasma cell disorder ( multiple myeloma). But it only says suspicious band so here is what you should do to confirm it

1. Bone marrow aspiration and biopsy
2. X ray of the skull lateral view to look for lytic lesions
3. Urine for bence XXXXXXX proteins
4. If all reports are negative and clinically there is still a suspicion of multiple myelome then I would have done a bone marrow biopsy

I hope I was of help, if you have any further queries please get back to me

Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Rakesh Madhyastha (8 hours later)

Hello Dr

I did not mention that I have a Stage 3 kidney disease, have had anemia as well for 3 years now, anemia is being treated with Iron i fusions as well as "as needed" epo.
Hemoglobin is still about a 9.0 with treatments and kidney disease is remaining stable with controlled high blood pressure, these factors will most likely play into the picture with possibilty of having M Myeloma i'm assuming, although what, if any difference it would make I am not sure. Your thoughts Dr?

Answered by Dr. Rakesh Madhyastha (6 hours later)

Brief Answer:
Follow up

Detailed Answer:
Hello

Thanks for getting back with more info. Epo plus iron is the best way to treat anemia in CKD and it prevents blood transfusions.
There are chances that MM can worsen the CKD in many ways, most importantly calcium induced dehydration however I am really not sure you have MM at all. Please follow the diagnostics steps I have jotted down for you, be positive.

Regards

Note: For further queries related to kidney problems and comprehensive renal care, talk to a Nephrologist. Click here to Book a Consultation.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar