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What Does This Blood Test Result Indicate?
Question: Can you please read these blood tests and let me know what your diagnosis is?
Brief Answer:
You could be having gluten enteropathy
Detailed Answer:
Thanks for asking on HealthcareMagic.
I have gone carefully through the attached reports. I would need to ask you the reasons for getting the tests done. Except for (anti) transglutaminase antibodies, the test reports are fine. Anti-transglutaminase antibodies are found in celiac disease and may play a role in the small bowel damage in response to dietary gliadin that characterises this condition. Gliadin is a class of proteins that is a component of gluten and is present in wheat and several other cereals of wheat category. So you need to restrict the intake of gluten containing foods.
Recent research indicates that sufferers from neurological diseases like Huntington's and Parkinson's may have unusually high levels of tissue transglutaminase. So, clinical correlation is required in this aspect.
Diagnosis is not something that can be done based on reports alone. We treat patients, not reports.
Hope that helps.
Regards
You could be having gluten enteropathy
Detailed Answer:
Thanks for asking on HealthcareMagic.
I have gone carefully through the attached reports. I would need to ask you the reasons for getting the tests done. Except for (anti) transglutaminase antibodies, the test reports are fine. Anti-transglutaminase antibodies are found in celiac disease and may play a role in the small bowel damage in response to dietary gliadin that characterises this condition. Gliadin is a class of proteins that is a component of gluten and is present in wheat and several other cereals of wheat category. So you need to restrict the intake of gluten containing foods.
Recent research indicates that sufferers from neurological diseases like Huntington's and Parkinson's may have unusually high levels of tissue transglutaminase. So, clinical correlation is required in this aspect.
Diagnosis is not something that can be done based on reports alone. We treat patients, not reports.
Hope that helps.
Regards
Above answer was peer-reviewed by :
Dr. Yogesh D
I got tests because i had terrible diarrhea. I think that was caused by vibrio as you can see in the results. My doctor told me the anti-transglutaminase is not urgent. He said once the vibrio passes through my system i will feel better. Essentially he is saying the diarrhea was caused by the vibrio and not the gluten. Do you suggest i pursue the gluten results??
Brief Answer:
The diarrhea could be related to gluten too
Detailed Answer:
Thanks for writing back.
Your doctor has correctly stated that Vibrio parahemolyticus passes off through the gastrointestinal tract and does not need to be treated with antibiotics. That is the reason that I did not point out separately about it. All you need to do is to take ORS (oral rehydration solution) to make up for the salt and water lost.
I would suggest you to follow up with the the anti-transglutaminase. You need to avoid gluten containing foods. A simple google search will give you what to avoid and how.
Regards
The diarrhea could be related to gluten too
Detailed Answer:
Thanks for writing back.
Your doctor has correctly stated that Vibrio parahemolyticus passes off through the gastrointestinal tract and does not need to be treated with antibiotics. That is the reason that I did not point out separately about it. All you need to do is to take ORS (oral rehydration solution) to make up for the salt and water lost.
I would suggest you to follow up with the the anti-transglutaminase. You need to avoid gluten containing foods. A simple google search will give you what to avoid and how.
Regards
Above answer was peer-reviewed by :
Dr. Yogesh D
Ok.. Is there another test inshould ask for to rule out celiac disease. I am looking to get to the bottom of the gluten issue. My doctor said since there is vibrio he would rather focus on that. He suggests keep a normal diet and if i develop symptoms once the vibrio passes he would recommend further testing. He said since i have never had an issue with gluten before that its not serious. I would still like to rule out celiac disease and want to know what tests i can get to get 100% confirmation.
Brief Answer:
Try a gluten free diet first.
Detailed Answer:
Sorry for not being able to respond earlier.
Rather than going for tests to discern celiac disease, I would suggest you to refrain from taking gluten containing foods for at least 15 days and see if you remain better. It is only after the passing of the present episode and the trial of modified food regime thereafter that you should think of further testing.
Immunoglobulin A (IgA) anti-tissue transglutaminase antibody is the single preferred test for detection of celiac disease. If abnormally elevated levels of IgA endomysial and anti-tissue transglutaminase antibodies are found, you almost certainly have celiac disease. High levels of another antibody, anti-gliadin antibody (AGA), may also be detected, but they don't necessarily mean that you have celiac disease. However, anti-gliadin antibody levels are useful in monitoring response to treatment, because they will usually begin to fall within several months of successful treatment of celiac disease with a gluten-free diet. Similarly, anti-endomysial antibody levels decrease on a gluten-free diet and often become negative in treated patients.
Small intestine biopsy would give the most definitative diagnosis but I do not think that you need it. The following link should be helpful:
http://www.csaceliacs.org/diagnosis_of_celiac_disease.jsp
Regards
Try a gluten free diet first.
Detailed Answer:
Sorry for not being able to respond earlier.
Rather than going for tests to discern celiac disease, I would suggest you to refrain from taking gluten containing foods for at least 15 days and see if you remain better. It is only after the passing of the present episode and the trial of modified food regime thereafter that you should think of further testing.
Immunoglobulin A (IgA) anti-tissue transglutaminase antibody is the single preferred test for detection of celiac disease. If abnormally elevated levels of IgA endomysial and anti-tissue transglutaminase antibodies are found, you almost certainly have celiac disease. High levels of another antibody, anti-gliadin antibody (AGA), may also be detected, but they don't necessarily mean that you have celiac disease. However, anti-gliadin antibody levels are useful in monitoring response to treatment, because they will usually begin to fall within several months of successful treatment of celiac disease with a gluten-free diet. Similarly, anti-endomysial antibody levels decrease on a gluten-free diet and often become negative in treated patients.
Small intestine biopsy would give the most definitative diagnosis but I do not think that you need it. The following link should be helpful:
http://www.csaceliacs.org/diagnosis_of_celiac_disease.jsp
Regards
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Above answer was peer-reviewed by :
Dr. Shanthi.E
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