
What Is Bladder Outlet Obstruction?

obstructive urinary voiding symptons
Detailed Answer:
Hi,
When a patient gas symptoms of slow urunary flow, sense if incomplete evacuation of urine, with intermittent stream with straining to void urine, he is suspected if having bladder outlet obstruction which us fairly common in older makes due to prostate and due to a tight bladder neck in young men.
Common tests to diagnose this would be an ultrasound scan for KUB, I.e kidneys and bladder followed by a uroflowmetry and an estimate of post-boid residue urine. Quite a few patients would respond to medicines like Flomax while some might require surgery.
Some individuals could have similar symptoms due to a weak bladder muscle rather than an outlet obstruction and the net effect is the same, but these patients will not respond to drugs like Flomax and an ultrasound might not pick an enlarged prostate though there could be significant urine residue. Such patients are advised a urodynamic test which will correctly identify if the bladder outlet is indeed obstructed or if the muscle is weak.
Hope I have been able to answer your questions.
Regards


Aunt has forgetfulness and wants to go back and get the Ditropan again. Is it okay for her to have Ditropan if she wants too for her quality of life.
Quality of life issues important
Detailed Answer:
Hi,
I guess the MD who put your aunt on the drugs like DiTropan / Myrbetriq must have hoped for an improvement in the symptoms of your aunt, and if your aunt felt that there was no response with the medication, i.e. no reduction in urinary frequency, urgency or leak episodes, it would qualify as a failure.
However, even in the best of circumstances, these drugs are not effective fully, and therefore even a partial sense of control will help patients win back their self esteem, and a reduction of leak episodes will often cause them to accept minor side-effects which most of these drugs have such as dry mouth.
The other options available include an injection of botulinum Toxin via cystoscopy but you should realize this will give only a temporary relief, and a year from the day of injection, things could be back to square one.
Diapers are never a bad idea, and if there is an issue of restricted mobility, night time diapers might reduce chances of skin maceration. Also, elderly people have a tendency to slip and fall in their efforts to reach the toilet fast, and often land up with a broken hip which could be disastrous. So lifestyle changes could also help such as relocating her bed to be as close to the toilet as possible, and restricting fluids in the evenings, especially coffee, tea. Timed voiding, i.e going to the toilet at a particular time, irrespective of the urge to need to evacuate, and later gradually increasing the intervals between voids could also help regain control
Drugs are several in the market, and if one does not work, it does not mean that others will not. I guess she can experiment with several other brands available such as vesicare, and see which suites her the best and at what dosage.
Hope I have been of help.
Regards.


Urinary retention likely if associated obstruction
Detailed Answer:
Hi,
Ditropan belongs to a class of drugs known as anti-cholinergics. One of the effects of the drug is to reduce the contractility of bladder. However, if a patient has a pre-existing bladder outlet obstruction, and the associated irritability has caused urinary urgency and frequency, placing them on Ditropan could cause an increase in the risk of urinary retention where patients will be unable to void urine despite the urge to do so. This is what your Urologist probably feared. Hence, one of the precautions we do take before placing patients on drugs like Ditropan would be to see if the urine flow rate is adequate,.i.e. comparable to people of that age for which standardized nomograms exist, and secondly check if there is significant post-void residue. If flow rate is adequate, and residual urine is not very high, there is no reason to withhold drugs like Ditropan which seem to have reduced the night time urge to toilet, while there might be increased urine staying back in the bladder after she voids, as long as it is not unacceptably high.
As I did mention earlier, Ditropan is a fairly old drug, and there have been newer molecules which have come in the market over the past 6-8 years like Vesicare which I did mention earlier or Darifenacin or Trospium which are probably more efficacious while not causing the kind of problems which can happen with Ditropan. Hard candy chewing is a perfectly acceptable solution for relief of the dry mouth rather than increase intake of fluids which can worsen the problem. Personally, I have never put my patients on Myrbetriq yet.
Hope i have been able to clarify your doubts.

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