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What Is The Difference Between Ambien And Zolpidem?

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Posted on Mon, 6 Jul 2015
Question: What is the difference in the active and inactive ingredients in Ambien and its generic, Zolpidem? As Ambien is very expensive but the generic makes me wake up irritable. Is that possible?
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Answered by Dr. Shubham Mehta (4 hours later)
Brief Answer:
no pharmacological difference.

Detailed Answer:
Hello
Welcome to HCM.
I understand your concerns.

Pharmacologically, there is no difference between ambien and generic zolpidem.

However, in practical experience, some patients do complain of differences in efficacy and tolerability of the two for unexplained reasons.

Possibly, the generic zolpidem is not working for you.

Kindly discuss this with your doctor.

I wish you well.
Take care.
Thanks.
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shubham Mehta

Psychiatrist

Practicing since :2008

Answered : 2144 Questions

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What Is The Difference Between Ambien And Zolpidem?

Brief Answer: no pharmacological difference. Detailed Answer: Hello Welcome to HCM. I understand your concerns. Pharmacologically, there is no difference between ambien and generic zolpidem. However, in practical experience, some patients do complain of differences in efficacy and tolerability of the two for unexplained reasons. Possibly, the generic zolpidem is not working for you. Kindly discuss this with your doctor. I wish you well. Take care. Thanks.