Sign-in to Ask A Doctor - 24x7
OR
Sign in with Google
Will Amphotericin B Or Fluconazole Help Better To Treat Fungal Infections?
Question: have family outside the country with sarcoidosis now onconcious with fungus in csf . DRS not sure whether to start amphotericin B or FUCONAZOL IV
ok thanks. note he has sarcoidosis and on prednisone
ok thanks. note he has sarcoidosis and on prednisone
Brief Answer:
Fluconazol may be started.
Detailed Answer:
Hello and thanks for using HCM.
I have read your question and understand your concerns.
Both antifungal drugs may be used, but optional treatment should be guided by antibiogram.
In my opinion, since fluconazol belongs to newer antifungal drugs and is taken i.v., should be used.
A brain MRI also is necessary to evaluate the extent of the fungal infection.
Hope you found the answer helpful.
Take care.
Fluconazol may be started.
Detailed Answer:
Hello and thanks for using HCM.
I have read your question and understand your concerns.
Both antifungal drugs may be used, but optional treatment should be guided by antibiogram.
In my opinion, since fluconazol belongs to newer antifungal drugs and is taken i.v., should be used.
A brain MRI also is necessary to evaluate the extent of the fungal infection.
Hope you found the answer helpful.
Take care.
Above answer was peer-reviewed by :
Dr. Vaishalee Punj
he is now on iv fluconazol but iam not sure if 400mg is adequate a six feet adult approximately 190lb. pls. I like to know the recommended MG/KG, HOW OFTEN eg q12 or q8 etc,how long can he be on the treatment or duration of the treatment.
I thank you for help.
I thank you for help.
Brief Answer:
Doses for 24 hours explained below.
Detailed Answer:
Welcome back.
Fluconazole dose varies from 6 mg/kg to 12 mg/kg/daily.
Doses to treat central nervous system involvement in adults may be from 400 to 800 mg fluconazole daily for several weeks.
However, this can be adjusted to patient's condition and this is a decision that belongs to the treating Doctor.
Hope I helped you.
Kind regards.
Doses for 24 hours explained below.
Detailed Answer:
Welcome back.
Fluconazole dose varies from 6 mg/kg to 12 mg/kg/daily.
Doses to treat central nervous system involvement in adults may be from 400 to 800 mg fluconazole daily for several weeks.
However, this can be adjusted to patient's condition and this is a decision that belongs to the treating Doctor.
Hope I helped you.
Kind regards.
Above answer was peer-reviewed by :
Dr. Remy Koshy
Answered by
Get personalised answers from verified doctor in minutes across 80+ specialties
