
Will Oxandrolone Cause Much Damage To Liver Enzymes? How Long Until Enzymes Return To Normal?

Thanks for posting your query. I am happy to address your questions, Oxandrolone is relatively quick to be metabolized by the body with concentrations of the drug falling rapidly after ten to eighteen hours after administration and Liver enzymes will likely rise while a user is taking this compound, however the actual damage that occurs to the liver is very minor to non-existant. As it has a very short half life, thus to keep blood levels stable twice per day dose is more efficient as once per day administration would result in very little of the medication still being active in the body once a 24 hour period has passed. To be more cautious would recommend you get your liver enzymes checked after a week (for your satisfaction) and it should be in the normal range. Hope I have answered your query. If you have any further questions, I will be happy to help. Thanks


Thanks for your kind response, using low dosages of this compound has minimal interference with natural testosterone production. Likewise when it is used alone in small amounts there is typically no need for ancillary drugs like tamoxifen. This has a lot to do with the fact that it does not convert to estrogen, which we know has an extremely profound effect on endogenous hormone production. Without estrogen to trigger negative feedback, we seem to note a higher threshold before inhibition is noted. But at higher dosages of course, a suppression of natural testosterone levels will still occur with this drug as with any anabolic/androgenic steroid and therefore require post cycle therapy. If you have no further clarifications, will request you to kindly close the query and rate it. Thanks


Thanks for your kind response, aromatase is the enzyme that converts male hormones to female estrogens. It is the primary way men create estrogen and failure to control this on cycles of aromatizing androgens may produce very unsightly side effects. The most commonly used over the counter (OTC) anti-estrogens work through inhibiting this enzyme is Androstatriene-Dione (ATD) or Post Cycle Matrix. ATD is a supplement that gained huge exposure in numerous OTC PCT products over the past several years. It is a suicidal inhibitor of the aromatase enzyme, meaning that once the drug has been discontinued enzyme levels slowly return to baseline. Suicidal inhibitors are often preferred because there is no “rebound” in estrogens after coming off. Post Cycle Matrix is designed to help balance hormone levels during the period of Post Cycle Therapy (PCT) and can decrease estrogen in males. Also there is Formestane which will convert to the substance 4-hydroxytestosterone within the body, and this may make it hinder recovery if used during PCT. Formestane is another suicidal inhibitor of the aromatase enzyme. If you have no further clarifications, will request you to kindly close the query and rate it. Thanks

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