42 y/o F, 5'8 185lbs, (formerly 155 norm) chronic fatigue, even after sleep, NO appetite, force self to eat, tendency to hypoglycemia since teens,but weight gain, hx back pain, 1-2+ bilateral edema legs (4+ years), anxiety, depressed, high stress for years, job loss, SAHM 3 & 1 yr olds, hypothyroid Dx 04/14 Synthroid brought TSH from 12.34 to 1. Feel terrible ALL the time~ incapable of handling any stress, extreme irritability, used to enjoy life, now NO energy. Endo/colonoscopy yesterday for +GERD and internal hemmorhoids, hx bleeding. Lower legs U/S 2 weeks ago- Neg venous insufficiency. Sometimes palps, ECHO when preg- some PVC's. Food allergies. Just started sleeping through night few weeks ago. MD unsure what to do.