Can elevated AST/ ALT levels be indicative of having had a seizure? (AST = 204 ALT=608) My son is 20, and 135lbs, and has a history of seizures. He had a car accident, and is being cited for DUI, however he insists he was not impaired. I remembered from his first seizure, after seeing on the blood work that his liver enzymes were really high, the doctor indicated that the seizure may have caused the high levels, and it should go down. She had him tested for hep C for assurance and it came back negative. He also is a chronic pain patient. He takes daily meds, ( oxycodone , soma, lorazepam) but these have not affected his liver so far. He also had not had any medication for a few days before the accident.