I can't believe your name is Grief. My question is as follows. My mother has all indications of MDS but has not had a marrow biopsy. She is 77 and does not want aggressive treatment such as chemotherapy. She is minimally diabetic - handled with diet. She is on medication for high blood pressure and has been for years. I am noticing shortness of breath resulting in limitations. I am noticing things like being unable to lift her leg to get in or out of the bathtub. Tonight I noticed her feet were swollen but no discoloration or petechiae. I don't want to alarm her. What do I do next? Is this an indicator of progression to Acute Myeloid Leukemia? What kind of prognosis should I expect? Is it time for me to bring her to live with me? She is about 8 miles from me now.