I have had psoriasis my whole life and unfortunately handed it down to my three children 4,3,and 6 months . My question is regarding the mmr vaccine . Since psoriasis is an auto-immune system disease is it still safe to receive the mmr vaccination ? The mmr vaccination is a live vaccine is there any risk of contracting the diseases because of having a compromised immune system ? I myself have also been tested during pregnancy after 2 doses of the mmr vaccine prior to pregnancy and have been told 3 times that even tho I had the vaccinations I am not immune to rubella . In people with psoriasis are vaccinations compromised or sometimes less effective and unresponsive ?