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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Blood Results Show Allergic Drug Eruption, Urticaria, Mixed Cell Inflammatory Infiltrate With Eosinophils. Meaning ?

I have red cells, white Cells and platelets low, with constant rash and funges, who presented fevers, headache, weight loss A dermatologist refer to an internist then to do a biopsy which describe a perivascular lymphocytic infiltrate with eosiphilosis Comments: the differencial diagnosis include allergic drug eruption, urticaria and other hypersensivity reaction. diagnosis: mixed- cell inflammatory infiltrate with eosinophils. I need to know if those labs results and symptoms demonstrate a possible vhi
posted on Wed, 21 Nov 2012
Twitter Wed, 21 Nov 2012 Answered on
Twitter Wed, 21 Nov 2012 Last reviewed on
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General & Family Physician,  's  Response
Dear Concerned.,

Thanks for writing to us.

You may be having allergy to Drugs that you have been using for fungal infection.Most of the antifungals are drugs which interact with Alcohol.Do you drink when you are on Prescription drugs?If it is yes,this could be one such Drug to Drug Hypersensitivity Reactions.

Your constant weight loss could be a pointer to Helminthiasis//worms infestation .The toxins of various worms(round worm/hook worm/pin worm/thread worm etc) in the intestine produce the above blood picture of Eosinophilia( more than 400/cmm of blood sample).

Kindly get your Stools examined for Ova/Cysts of Parasites and get treated with Anti-helminthics such as Albendazole/Ivermectin etc

After the treatment again undergo investigation to see the effect of therapy.

"an Eosinophilic granuloma has to be differentiated from acute peripheral Eosinophilia by clinical correlation" by treating MD.

Wishing you Speedy recovery.,

Best regards.,

Dr Lt Cdr ASN Bhushan.
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Blood Results Show Allergic Drug Eruption, Urticaria, Mixed Cell Inflammatory Infiltrate With Eosinophils. Meaning ?

Dear Concerned., Thanks for writing to us. You may be having allergy to Drugs that you have been using for fungal infection.Most of the antifungals are drugs which interact with Alcohol.Do you drink when you are on Prescription drugs?If it is yes,this could be one such Drug to Drug Hypersensitivity Reactions. Your constant weight loss could be a pointer to Helminthiasis//worms infestation .The toxins of various worms(round worm/hook worm/pin worm/thread worm etc) in the intestine produce the above blood picture of Eosinophilia( more than 400/cmm of blood sample). Kindly get your Stools examined for Ova/Cysts of Parasites and get treated with Anti-helminthics such as Albendazole/Ivermectin etc After the treatment again undergo investigation to see the effect of therapy. an Eosinophilic granuloma has to be differentiated from acute peripheral Eosinophilia by clinical correlation by treating MD. Wishing you Speedy recovery., Best regards., Dr Lt Cdr ASN Bhushan.