Hi There!I used my Drug Nutrient Interaction checker and did not find adverse effects on the lipids. It doesn t mean there aren t any, they just aren t listed and I don t see any reason off hand that they would. Flaxseed if taken with the husk can decrease absorption of both medications from the bulk forming activity from flaxseed. Be careful of your lipid ratios. You need a small amount of monounsaturates, some essential polyunsaturated fats and less than 10% of calories as saturated fat. Essential Fatty Acid Alpha-linolenic acid is a kind of omega-3 fatty acid found in plants. It is found in flaxseed oil, and in canola, soy, perilla, and walnut oils. Alpha-linolenic acid is similar to the omega-3 fatty acids that are in fish oil, called eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Linoleic acid is a type of fat, or fatty acid, found in vegetable oils, nuts, seeds and animal products. An essential omega-6 fatty acid, linoleic acid is required by the human body in small amounts. Most people get 6x the linoleic acid they need but are deficient in the omega 3 or alpha-linolenic acid. High intakes of linoleic acid may increase inflammation, which can damage the endothelial cells lining your arteries and increase your risk of heart disease In addition, animal studies suggest it may promote the spread of cancer from breast cells to other tissues, including the lungs. Bottom Line: Processed vegetable and seed oils contain omega-6 fats. Most people are eating too much of these fats already, which may lead to several health problems. So, I suggest a small adjustment in the ratios of the types of fats you are consuming unrelated to your blood fats. Regards, Kathryn Shattler, MS,RDN