Hi, Thanks for posting in HCM. Berbesta contains Berberine , a chemical found in several plants. People take berberine for heart failure. Herbs containing berberine have been used in Chinese medicine to treat diabetes for thousands of years. There is early evidence that berberine can help lower cholesterol levels in people with high cholesterol. People apply berberine directly to the skin to treat burns and to the eye to treat bacterial infection trachoma. Berberine extract has been shown to help individuals who have PCOS. However, weather it would regularize the periods or if it does so, the mechanism is not known. Berberine is possibly safe for most adults for short-term use when taken orally or applied to the skin. It can lower blood sugar or blood pressure as possible side effect. Hope the information provided would be useful. Wish you good health.