I had a complete hysterectomy about 3 years ago and have never seemed to recover/feel like my old self ever since. I took whatever hormone that my doctor prescribed (orally) for about 3-6 months. It made me gain about 20lbs. I switched to the Vivelle dot patch .075 and lost the weight, but have battled all the symptoms associated with low estrogen especially depression and cognitive/memory issues. I ve been through the wringer so to speak over the last two years. I had my hormone levels tested. I had high DHEA and prolactin levels. They put me on cabergoline (0.5 mg 2x a week). I am also taking Effexor (150 mg). It s helped a little but I still am not myself. Could this patch just not be strong enough or what? I m so sorry. I did not realize there was a charge for this! Please disregard.