Dear Sir, I am a parkingson s patient about six years and having S1 Disc problems, i had leg edema severly and unable to move. My blood reports shows ESR 40mm/hr and C Reactive Protein 18.02mg/L (Positive), Cheser Negative (Latex) (N, lessthan20IU/ml). request Orthopedic opinion. regards, N.Selvakumar.