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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Fluctuating SGPT, Taken Lamivir. What Is My Current Condition?

Dear Sir, I m 40 years male found HBsAg + in 2006 HBeAg negative but SGPT was 79, a bit fatty liver , HBV DNA + 1.0 x 10 (4) then I go under medication (Lamivir 100mg) after 3 years in August 2009 HBV DNA found negative but continue medication. Further test in May 2010 HBV DNA found negative then I leave medication, meanwhile SGPT always fluctuating in between 50-90. after leaving medication SGPT fluctuated same as earlier. Recently SGPT increased to 120 in last August 2 days back SGPT found 124. May I know what is my current condition and what should I do?
Fri, 12 Sep 2014
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Gastroenterologist 's  Response
Hello,
Your SGPT levels are almost three times the upper limit of normal, this suggests reactivation of the disease. I would advise you to Get a HBV DNA viral load done and in case it is detectable you would need to start treatment. It would have to be a medicine other than lamivudine as now better drugs are available.
I would also suggest you get a USG and complete LFT done.
I would advise you to consult a gastroenterologist who would guide you regarding the further management plan
Hope this helps
Do get back in case you have further queries
Regards
Dr Samir Patil
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Fluctuating SGPT, Taken Lamivir. What Is My Current Condition?

Hello, Your SGPT levels are almost three times the upper limit of normal, this suggests reactivation of the disease. I would advise you to Get a HBV DNA viral load done and in case it is detectable you would need to start treatment. It would have to be a medicine other than lamivudine as now better drugs are available. I would also suggest you get a USG and complete LFT done. I would advise you to consult a gastroenterologist who would guide you regarding the further management plan Hope this helps Do get back in case you have further queries Regards Dr Samir Patil