Hallow Dear, By stopping tri-sprintec midcycle, the pregnancy cannot be guaranteed. However, you may expect pregnancy in the subsequent cycle. There is a school which believes that after discontinuing the oral contraceptive pills, if there is any pregnancy within six months, the chances of miscarriage are rather high. So you may take your informed decision whether to go for pregnancy from next cycle or delay it for next six months. I feel, no harm in going for pregnancy. There is no risk of foetal abnormality. Hope this helps you, Dr. Nishikant Shrotri