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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can I Rely On Chemotherapy For Addison S Disease And Breast Cancer?

Hi I have addison s disease and breast cancer, just had my 1st round of chemotherapy 21 day cycle, for 4 cycles , then am supposed to do weekly taxol, He you treated any with addison s, l have 7 lymph nodes removed 4 were bad.. l can ope just with the chemo being on fludro and hydro stress dose, then being dropped down to normal dose, but am so not sure how my body will cope doing stress doses weekly, have you tr eated any 1 that has addison s and breast cancer, any suggestions or advice would be greatly appreciated
Wed, 10 Jan 2018
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Oncologist 's  Response
Hi

After hearing your history i would advise you to continue chemotherapy with taxol.

It contains paclitaxel a very good drug for the treatment of breast cancer.

Common side effects include nausea and vomiting, loss of appetite, change in taste, thinned or brittle hair, pain in the joints of the arms or legs lasting two to three days, changes in the color of the nails, and tingling in the hands or toes. More serious side effects such as unusual bruising or bleeding, pain/redness/swelling at the injection site, hand-foot syndrome, change in normal bowel habits for more than two days, fever, chills, cough, sore throat, difficulty swallowing, dizziness, shortness of breath, severe exhaustion, skin rash, facial flushing, female infertility by ovarian damage, and chest pain can also occur. Neuropathy may also occur.
These side effcets can be managed symptomatically.

So all the best.

Treatment for Addison's disease involves hormone replacement therapy to correct the levels of steroid hormones your body isn't producing. Some options for treatment include:

Oral corticosteroids. Hydrocortisone (Cortef), prednisone or cortisone acetate may be used to replace cortisol. Your doctor may prescribe fludrocortisone to replace aldosterone.
Corticosteroid injections. If you're ill with vomiting and can't retain oral medications, injections may be needed.
An ample amount of sodium is recommended, especially during heavy exercise, when the weather is hot or if you have gastrointestinal upsets, such as diarrhea. Your doctor will also suggest a temporary increase in your dosage if you're facing a stressful situation, such as an operation, an infection or a minor illness.

regards

DR DE

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Can I Rely On Chemotherapy For Addison S Disease And Breast Cancer?

Hi After hearing your history i would advise you to continue chemotherapy with taxol. It contains paclitaxel a very good drug for the treatment of breast cancer. Common side effects include nausea and vomiting, loss of appetite, change in taste, thinned or brittle hair, pain in the joints of the arms or legs lasting two to three days, changes in the color of the nails, and tingling in the hands or toes. More serious side effects such as unusual bruising or bleeding, pain/redness/swelling at the injection site, hand-foot syndrome, change in normal bowel habits for more than two days, fever, chills, cough, sore throat, difficulty swallowing, dizziness, shortness of breath, severe exhaustion, skin rash, facial flushing, female infertility by ovarian damage, and chest pain can also occur. Neuropathy may also occur. These side effcets can be managed symptomatically. So all the best. Treatment for Addison s disease involves hormone replacement therapy to correct the levels of steroid hormones your body isn t producing. Some options for treatment include: Oral corticosteroids. Hydrocortisone (Cortef), prednisone or cortisone acetate may be used to replace cortisol. Your doctor may prescribe fludrocortisone to replace aldosterone. Corticosteroid injections. If you re ill with vomiting and can t retain oral medications, injections may be needed. An ample amount of sodium is recommended, especially during heavy exercise, when the weather is hot or if you have gastrointestinal upsets, such as diarrhea. Your doctor will also suggest a temporary increase in your dosage if you re facing a stressful situation, such as an operation, an infection or a minor illness. regards DR DE