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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can An Online Doctor Explain The Histopathology Report ?

Dear Sir,
MY Histopathology report says : Gross Description: Multiple cores of tissues
and
Microscopic Description says;
Metastatic carcinoma consistent with primary origin in an andrenocortical neoplasm
The Tumor cells express synaptophysin focally.
They are immunonegative for CK, Melan A, chromogranins, HSA and inhibin,
The Mib-1 Prolieferation index is 5%

Are these reports sensitive
Tue, 30 Apr 2013
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Pathologist and Microbiologist 's  Response
Hello,

You have not mentioned site of biopsy .Whatever may be site of biopsy this report shows malignancy there which has most probably come from adrenocortical area .it means that cancer has spread and has reached the site of biopsy. Adrenocortical area is situated just above kidney . Consult your oncologist for further guidance.
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Orthopaedic Surgeon Dr. Sunil Kumar Srivastava's  Response
This report indicates that your adrenal gland is affected.it is situated above the kidneys and its basic function is maintenance of electrolyte and water balance and production of hormones for general metabolism etc.
report shows that spread may have occurred to surrounding areas also.
You must seek help of both endocrinologist and an oncologist
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Can An Online Doctor Explain The Histopathology Report ?

Hello, You have not mentioned site of biopsy .Whatever may be site of biopsy this report shows malignancy there which has most probably come from adrenocortical area .it means that cancer has spread and has reached the site of biopsy. Adrenocortical area is situated just above kidney . Consult your oncologist for further guidance.