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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Aspirin Cause Allergy Related Issues?

Hi, I have inherited a very allergenic system. The only way I have been able to keep my sensitivities under control is to rotate all my foods. When my allergist recommened this strategy, he also said to stay away from Penicillin and asprin. I understand the Penicillin as I have 2 syblings and a parent that developed allergies to it. But, I don t understand the aspirin. Now that I am on Celebrex, I am a little concerned about the aspirin issue , as it sounds as though Celebrex and Aspirin might be related. Can there be a problem?
Fri, 28 Feb 2014
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Anesthesiologist,  's  Response
Hello,
I have gone through your query and understand your concern.
Yes. You can take Celecoxib.
Both are related by the way of,both are NonSteroidal Antiinflammatory drugs and Pain killers.
Both are not related chemically and structurally.
BOth act by inhibiting cyclooxygenases. There are two cyclooxygenases - cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2).
Aspirin inhibits both and Celecoxib inhibits COX-2 selectively.

Aspirin allergy is mostly due to component called salicylate. Thus you should avoid other salicylate containing drugs.
Celecoxib does not contain salicylates and it is also safe in peoples allergic to Aspirin and most of NSAIDs.

Hope this helps.
Please write back for further queries.
Wishing you good health.
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Can Aspirin Cause Allergy Related Issues?

Hello, I have gone through your query and understand your concern. Yes. You can take Celecoxib. Both are related by the way of,both are NonSteroidal Antiinflammatory drugs and Pain killers. Both are not related chemically and structurally. BOth act by inhibiting cyclooxygenases. There are two cyclooxygenases - cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). Aspirin inhibits both and Celecoxib inhibits COX-2 selectively. Aspirin allergy is mostly due to component called salicylate. Thus you should avoid other salicylate containing drugs. Celecoxib does not contain salicylates and it is also safe in peoples allergic to Aspirin and most of NSAIDs. Hope this helps. Please write back for further queries. Wishing you good health.