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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Hereditary Spastic Paraplegia Affect PSA Levels? Have Prostate Cancer

Is there any possibility that Hereditary spastic paraplegia can effect PSA levels? I have been diagnosed with Prostate Cancer . My urologist indicated that he found a small amount of Cancer in my biopsy,so I am having a prostatectomy in Oct. My PSA is 41 and he is unable to determine why it is so high. I have had an MRI, a CT scan, and a bone scan and they were all negative. The PSA is the driving force for his request that I have the surgery.
Fri, 13 Sep 2013
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Pathologist and Microbiologist 's  Response
Hi!
welcome to HCM!
Hereditary spastic paraplegia does not effect PSA levels
PSA or Prostate-specific antigen, is a protein produced by cells of the prostate gland.The higher a man’s PSA level, the more likely it is that he has prostate cancer however some men who have prostate cancer do not have elevated PSA.

In addition to prostate cancer, a number of benign (not cancerous) conditions can cause a man’s PSA level to rise. The most frequent are prostatitis and benign prostatic hyperplasia (BPH) or a urinary tract infection.
If a man who has no symptoms of prostate cancer but has an elevated PSA level, the doctor may recommend another PSA test to confirm.
If a man’s PSA level continues to rise or if a suspicious lump is detected during a DRE, the doctor may recommend imaging such as a transrectal ultrasound, x-rays, or cystoscopy a prostate biopsy.
Your PSA is high due to prostate disease itself
hope your queries are answered
take care!
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Can Hereditary Spastic Paraplegia Affect PSA Levels? Have Prostate Cancer

Hi! welcome to HCM! Hereditary spastic paraplegia does not effect PSA levels PSA or Prostate-specific antigen, is a protein produced by cells of the prostate gland.The higher a man’s PSA level, the more likely it is that he has prostate cancer however some men who have prostate cancer do not have elevated PSA. In addition to prostate cancer, a number of benign (not cancerous) conditions can cause a man’s PSA level to rise. The most frequent are prostatitis and benign prostatic hyperplasia (BPH) or a urinary tract infection. If a man who has no symptoms of prostate cancer but has an elevated PSA level, the doctor may recommend another PSA test to confirm. If a man’s PSA level continues to rise or if a suspicious lump is detected during a DRE, the doctor may recommend imaging such as a transrectal ultrasound, x-rays, or cystoscopy a prostate biopsy. Your PSA is high due to prostate disease itself hope your queries are answered take care!