I also take MS Contin 60 mg BID. How is this holding up with the Oxycodone 10/325, 4 times a day, as well as 6 tablespoons of paregoric per day. My back and knees still give me a fit, have had 3 spinal surgeries,both knees operated on, 4 heart attacks, triple by pass heart surgery, a stroke, heart failure, currently have my 2nd ICD which I have been shocked 2 times from (saved me both times). Thanks for listening Paul