Itching and skin rash upper thighs and buttock, is it lisinopril related? I was on Lisinopril for 2-3 weeks, developed awful cough, congestion , tightness around chest , half swollen throat , and now rash on upper thighs. Sometimes itch and sometimes not; but I am on antihistamines every day for mega allergies. Anyone else having this problem - it would be great to hear from you.